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TROPICAMIDE
SynDRA canonical compound SYN0023081 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CHRM4 |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
| Indication | cycloplegia diagnostic | mydriasis diagnostic |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- CHRM3
- CHRM4
- CHRM2
- CHRM5
- CHRM1
- CYP2C19
- CYP2C9
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM2 ANTAGONIST
- CHRM4 ANTAGONIST
- CHRM5 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- NR3C1
- NPY2R
- NPY1R
- NEIL2
- NEIL1
- MUTYH
- MPG
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MBD4
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- NR1I2
- OGG1
- HMGCR
- OPRD1
- USP1
- TDG
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ACM4
- ACM5
- CP19A
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- MDR1
Drug classes
- Cholinergic Antagonists
- Anticholinergic
- Cholinergic Agents
- Muscarinic Antagonists
- Mydriatics
- Neurotransmitter Agents
- Peripheral Nervous System Agents
ATC classes
- S01F · MYDRIATICS AND CYCLOPLEGICS
Cross-references
Synonyms
- MYDCOMBI
- MYDRIACYL
- MYDRIAFAIR
- Mydriacyl
- PAREMYD
- TROPICACYL
- bistropamide
- epitromina
- mydriacyl
- Tropicamida
- Bistropamide
- Tropicamidum
- Visumidriatic
- NSC-757372
- RO-1-7683
- Mydriafair
- Nods
- Tropicacyl
- Tropicamide component of mydcombi
- Tropicamide component of paremyd
- Epitromina
- Mydral
- Mydriaticum
- Mydrum
- OcuTropic
- Opticyl
- Paremyd
- Tropikamid
- Tropimil
- Akorn Brand of Tropicamide
- Alcon Brand of Tropicamide
- Bournonville Brand of Tropicamide
- Cahill May Roberts Brand of Tropicamide
- Chauvin Brand of Tropicamide
- Colircusi Tropicamida
- Medical Ophthalmics Brand of Tropicamide
- Minims tropicamide
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