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FLUOROMETHOLONE
SynDRA canonical compound SYN0023079 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
| Indication | eye inflammation |
|---|
| Disease area | ophthalmology |
|---|
All known targets
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- DRD1
- ACHE
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTT
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- NPY2R
- OPRD1
- HDAC6
- OPRK1
- TBXAS1
- TBXA2R
- TARDBP
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CFTR
- CP2C9
- CP3A4
- CP3A7
- DNMT1
- ESRRA
- GLI3
- IL1B
- NSD2
- PRGR
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Allergic Agents
- Anti-Inflammatory Agents
- Glucocorticoids
- Hormones
ATC classes
- S01B · ANTIINFLAMMATORY AGENTS
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- D07A · CORTICOSTEROIDS, PLAIN
- D10A · ANTI-ACNE PREPARATIONS FOR TOPICAL USE
- S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
Cross-references
Synonyms
- FLUOR-OP
- FML
- FML FORTE
- FML-S
- OXYLONE
- fluormetholon
- flumetholone
- flumetholon
- Fluorometolona
- NSC-33001
- Fluaton
- Fluor-op
- Fluorometholone component of fml-s
- Fml
- Fml forte
- Fml fte
- Fml-neo
- Oxylone
- Cortilet
- Cortisdin
- Delmeson
- Efflumidex
- Flucon
- Flumetholon
- Fluormetholon
- Fluormetholone
- Fluormetholonum
- Fluoromethalone
- Fluorometholonum
- Fluorometolone
- Fluoropos
- Loticort
- Trilcin
- Ursnon
- Alcon Brand of Fluorometholone
- FML Forte
- FML Liquifilm
Reported adverse events
- Keratitis
- Cushing's syndrome
- Glaucoma
- Stevens-Johnson syndrome
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