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TIOCONAZOLE
SynDRA canonical compound SYN0022989 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | sterol demethylase inhibitor |
|---|
| Indication | yeast infection |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP17A1
- CYP8B1
- Candi ERG11
- ERG11
Mechanisms of action (all sources)
- CYP8B1 INHIBITOR
- sterol demethylase inhibitor
- Candi ERG11 INHIBITOR
- ERG11 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ATG4A
- ADRB2
- PDE4D
- NR1I2
- GHSR
- ATG4B
- OPRK1
- SLC6A4
- OPRD1
- ADRA2C
- KCNH2
- ADRA1A
- ADORA3
- MAOA
- MC3R
- MC4R
- MLNR
- IDO1
- NPY1R
- NR3C1
- ADORA1
- PGR
- OPRM1
- PDE3A
- HTR2C
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- TBXA2R
- TDP1
- USP1
- HTR3A
- HRH3
- HTR2B
- CHRM3
- ADRA2A
- ADRA2B
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADA10
- GLI3
- TP53
- SYK
- SMAD3
- SMAD2
- PRGR
- NSD2
- NR1H4
- NF2L2
- KSYK
- HSPB1
- ESRRA
- ADA17
- ESR2
- CREB1
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- CP19A
- ANDR
- TSHR
Drug classes
- Azole Antifungal
- 14-alpha Demethylase Inhibitors
- Anti-Infective Agents
- Antifungal Agents
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Hormone Antagonists
- Metabolic Side Effects of Drugs and Substances
- Steroid Synthesis Inhibitors
ATC classes
- G01A · ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
- D01A · ANTIFUNGALS FOR TOPICAL USE
Cross-references
Synonyms
- TZ-3
- VAGISTAT-1
- Vagistat
- Vagistat-1
- UK-20,349
- UK-20349
- Tioconazol
- NSC-759169
- Trosyl
- Tz-3
- Fungibacid
- GyneCure
- Tioconazolum
- Trosyd
- Zoniden
- Trosyd AF
- Trosyd J
- Monistat 1
- Gyno-trosyd
- Tioconazol [INN-Spanish]
- Tioconazolum [INN-Latin]
- UK 20,349
- Vagistat-1 (TN)
- Tioconazole (JAN/USP/INN)
- Tioconazole [USAN:BAN:INN:JAN]
- tioconazole (usp-rs)
- UK 20349
- tioconazole (usp monograph)
- NSC 759169
- S57Y5X1117
- tioconazole (usp impurity)
- tioconazole (ep monograph)
- (+-)-Tioconazole
- DTXCID1026619
- trosid
- tioconazolo
- Trosderm
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