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ALEXIDINE
SynDRA canonical compound SYN0022894 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PTPMT1 |
|---|
| Mechanism of action | Phosphatidylglycerophosphatase inhibitor |
|---|
All known targets
- PTPMT1
- CXCR4
- TLR9
- bla(tem-2)
- rep
Mechanisms of action (all sources)
- Phosphatidylglycerophosphatase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALOX15
- APAF1
- POLH
- POLI
- POLK
- POU2F1
- PTH1R
- RAPGEF3
- RAPGEF4
- RGS4
- SAMHD1
- SLC22A3
- SLCO1B1
- SMAD3
- SMPD1
- SNCA
- TARDBP
- TDP1
- TMPRSS15
- TP53
- TSNAX
- UBE2N
- USP1
- USP2
- VDR
- PLA2G1B
- PIN1
- NFE2L2
- GBA1
- ATAD5
- ATG4B
- ATXN2
- BLM
- BRCA1
- CCR6
- CYP3A4
- EYA2
- FEN1
- GALC
- GLP1R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- PPP1CA
- IFNG
- IL1B
- KPNB1
- KSYK
- MDM2
- MDM4
- MDR1
- MITF
- MRGPRX1
- NSD2
- NTM1A
- NTMT1
- PA21B
- PE2R2
- PSDE
- IDHC
- RARA
- RPGF4
- SMAD2
- SSPN
- STK33
- SUMO1
- SYK
- TNNC1
- TNNI3
- TNNT2
- TOR1A
- TR10B
- TSHR
- UBP1
- IFNB1
- HS90A
- ACES
- CP2D6
- ACM1
- ACM4
- ADRB2
- ANDR
Cross-references
Synonyms
- bisguadine
- bisguanidine
- alexidine dihydrochloride
- Alexidina
- Bisguadine
- COMPOUND 904
- STERWIN 904
- WIN 21,904
- WIN-21904
- Compound 904
- Alexidinum
- Sterwin 904
- Win 21,904
- 1,1'-Hexamethylenebis(5-(2-ethylhexyl)biguanide)
- GVN71CAL3G
- 1-[N'-[6-[[amino-[[N'-(2-ethylhexyl)carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-(2-ethylhexyl)guanidine
- CHEBI:53661
- N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
- Bisguanidine
- 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-
- N,N''''-hexane-1,6-diylbis[N'-(2-ethylhexyl)(imidodicarbonimidic diamide)]
- N,N'-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
- Alexidine [USAN:INN]
- Alexidinum [INN-Latin]
- SMR001233329
- Alexidina [INN-Spanish]
- UNII-GVN71CAL3G
- Win 21-904
- EINECS 245-096-7
- Spectrum_000459
- ALEXIDINE [INN]
- ALEXIDINE [MI]
- Alexidine (USAN/INN)
- ALEXIDINE [USAN]
- Prestwick0_000777
- Prestwick1_000777
- Prestwick2_000777
- Prestwick3_000777
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