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DIETHYLPROPION
SynDRA canonical compound SYN0022891 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A2 |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- SLC6A3 INHIBITOR
- Dopamine transporter inhibitor
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
- SLC6A4 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2A
- PGR
- HTR2A
- KCNH2
- ADORA1
- MC4R
- HDAC6
- HRH1
- HRH2
- HRH3
- HTR1A
- HTR2B
- HTR2C
- HTR3A
- MAOA
- MC3R
- NPY1R
- MLNR
- GHSR
- NPY2R
- NR3C1
- NTSR1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PTGS2
- SAMHD1
- SLC29A1
- GIPR
- GCGR
- ADORA2A
- ESR2
- ADORA3
- ADRA1A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Sympathomimetic Amine Anorectic
- Anti-Obesity Agents
- Appetite Depressants
ATC classes
- A08A · ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
Cross-references
Synonyms
- DIETHYLPROPION HYDROCHLORIDE
- TENUATE
- TENUATE DOSPAN
- TEPANIL
- TEPANIL TEN-TAB
- Tenuate
- adiposon
- amfepramon
- amfepramone
- amphepramon
- amphepramone
- diethpropion
- diethylpropione
- nopropiophenone
- diethylpropion hydrochloride
- amfepramone hydrochloride
- diethylpropion HCl
- amfepramone HCl
- Amfepramone
- Anfepramona
- Anfepramone
- Anferpramon
- Diethylcathinone
- C06954
- D07444
- J4.327C
- Diethylpropione
- Amfepramon
- Tepanil
- Anorex
- Nopropiophenone
- Frekentine
- Amphepramon
- Amfepramonum
- Amphepramone
- Adiposon
- Tylinal
- Magrene
Reported adverse events
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