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PROPANTHELINE
SynDRA canonical compound SYN0022809 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CHRM1 |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
| Indication | peptic ulcer disease (PUD) |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- CHRM2 ANTAGONIST
- Muscarinic acetylcholine receptor M2 antagonist
- CHRM4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ACHE
- RECQL
- MDH1
- NFE2L2
- NFKB1
- OPRM1
- PDE3A
- PDE4A
- PGR
- PMP22
- PTGS1
- SAMHD1
- MAOA
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- SMN1
- TBXA2R
- TDP1
- MAPT
- LMNA
- ADORA3
- KDR
- ADRA1A
- ADRA2A
- APEX1
- AR
- ATAD5
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- DRD1
- DRD3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- ACM5
- ANDR
- CP1A2
- CP2D6
- MDR1
- PPARG
- RGS4
Drug classes
- Cholinergic Antagonists
- Anticholinergic
- Anti-Ulcer Agents
- Cholinergic Agents
- Gastrointestinal Agents
- Muscarinic Antagonists
- Neurotransmitter Agents
ATC classes
- A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
Cross-references
Synonyms
- PRO-BANTHINE
- PROPANTHELINE BROMIDE
- Probanthine
- propantheline bromide
- propanthelinium
- probanthine
- Propantheline cation
- Propantheline ion
- Corrigast
- Ercorax
- Ercotina
- Ketaman
- Kivatin
- Neometantyl
- Neopepulsan
- Pantas
- Pantheline
- Pervagal
- Probantine
- Prodixamon
- Propantel
- Propanthel
- Propanthelinium
- Propanthelinum
- Bromure de propantheline
- Bromuro de proantelina
- Propantelina bromuro
- Propantelina bromuro [DCIT];Propanthelini bromidum
- P 8891
- Bromure de propantheline [INN-French]
- Bromuro de proantelina [INN-Spanish]
- Pro-Banthine
- Pro-Gastron
- Propanthelini bromidum [INN-Latin]
- SC-3171
- Pro-Banthine (TN);Propantheline bromide (JP15/USP/INN)
- Propantheline bromide [USAN:INN:BAN:JAN]
- RefChem:56971
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