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SUVOREXANT
SynDRA canonical compound SYN0022220 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HCRTR2 |
|---|
| Mechanism of action | Orexin receptor antagonist |
|---|
All known targets
- HCRTR2
- HCRTR1
- Hcrtr1
- Hcrtr2
Mechanisms of action (all sources)
- Orexin receptor antagonist
- HCRTR2 ANTAGONIST
- HCRTR1 ANTAGONIST
- HCRTR2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ADORA2A
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- ADORA1
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC6A2
- SLC6A3
- SLC6A4
- HRH2
- HRH1
- GHSR
- BDKRB2
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- CCKAR
Drug classes
- Central Nervous System Agents
- Central Nervous System Depressants
- Hypnotics and Sedatives
- Neurotransmitter Agents
- Orexin Receptor Antagonists
- Sleep Aids, Pharmaceutical
- P-Glycoprotein Inhibitors
- Cytochrome P450 3A Inhibitors
- Orexin Receptor Antagonist
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
Cross-references
Synonyms
- BELSOMRA
- Belsomra
- MK-4305
- belsomra
- MK4305
- Suvorexant component of belsomra
- MK 4305
- UNII-081L192FO9
- Suvorexant (MK-4305)
- CHEMBL1083659
- CHEBI:82698
- 081L192FO9
- C23H23ClN6O2
- BELSOMRA COMPONENT SUVOREXANT
- suvorexantum
- RefChem:56329
- DTXCID0068107
- N05CM19
- MFCD22377755
- Suvorexant [USAN:INN]
- Belsomra (TN)
- SUV
- SUVOREXANT [MI]
- SUVOREXANT [INN]
- SUVOREXANT [JAN]
- Suvorexant (JAN/USAN)
- SUVOREXANT [USAN]
- Suvorexant; MK 4305
- SUVOREXANT [VANDF]
- SUVOREXANT [WHO-DD]
- orb146219
- GTPL2890
- SCHEMBL1586289
- SCHEMBL13372948
- SCHEMBL29357712
- SUVOREXANT [ORANGE BOOK]
- EX-A211
- JYTNQNCOQXFQPK-MRXNPFEDSA-N
Reported adverse events
- Abnormal dreams
- Cataplexy
- Cough
- Depression
- Dizziness
- Dry mouth
- Gastrointestinal disorder
- Hallucination
- Headache
- Somnolence
- Upper respiratory tract infection
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