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BENSERAZIDE
SynDRA canonical compound SYN0022033 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | DDC |
|---|
| Mechanism of action | DOPA decarboxylase inhibitor |
|---|
| Indication | Parkinson's Disease |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DDC
- CBS
- ESR2
- HK2
- SAE1
- UBA2
- mex-5
- pos-1
Mechanisms of action (all sources)
- DOPA decarboxylase inhibitor
- DDC INHIBITOR
- CBS INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS2
- NPY1R
- ESR1
- MAPT
- NR3C1
- NPY2R
- NPSR1
- NFE2L2
- MTOR
- MPHOSPH8
- MLNR
- MC4R
- MC3R
- ADORA1
- OPRD1
- MAOA
- LMNA
- KDM4E
- KDM4A
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- NTSR1
- OPRK1
- HRH3
- OPRM1
- USP1
- TDP1
- TBXA2R
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- RGS4
- POLI
- POLB
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3G
- NSD2
- TACC3
- SYK
- SIRPA
- SENP8
- RIN1
- PSIP1
- PRMT1
- PRGR
- PPBN
- PPBI
- PIP4K2A
- PAFA
- PABP1
- NTM1A
- MRGPRX1
- ABL1
- MPI
- MITF
- MCL1
- KSYK
- IF4H
- GSTO1
- G3P
- DLD
- CD47
- B2CL1
- ARRB1
- ARNT
- APAF
- ANDR
- UBE2N
Drug classes
- Anti-Dyskinesia Agents
- Antiparkinson Agents
- Central Nervous System Agents
- Dopamine Agents
- Enzyme Inhibitors
- Neurotransmitter Agents
Cross-references
Synonyms
- benserazide hydrochloride
- serazide
- benserazide HCl
- BENSERAZIDE HYDROCHLORIDE
- Benserazida
- Benserazide (as hydrochloride)
- Benserazide hcl
- Serazide
- NSC-755907
- RO-4-4602
- Benserazide component of madopar
- Benserazide component of prolopa
- Benseraszide
- Benserazidum
- Ro 4-4602
- Ro 44602
- DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide
- Benserazidum [INN-Latin]
- Benserazida [INN-Spanish]
- Benserazide [USAN:INN:BAN]
- DL-Seryltrihydroxybenzylhydrazine
- C10H15N3O5
- BRN 3984490
- DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
- CHEBI:64187
- DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
- Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-
- DL-serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
- Ro 4 4602
- MADOPAR COMPONENT BENSERAZIDE
- PROLOPA COMPONENT BENSERAZIDE
- NSC 755907
- Seryltrihydroxybenzylhydrazine
- Seryltrihydroxy Benzylhydrazine
- Benzylhydrazine, Seryltrihydroxy
- RefChem:561256
- DTXCID302651
- UNII-762OS3ZEJU
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