← SynDRA

CEFUROXIME AXETIL

SynDRA canonical compound SYN0021767 — structure-anchored drug synonym record

All known targets

• dacA
• dacB
• dacC
• ftsI
• mrcA
• mrcB
• mrdA
• pbpA
• CA2
• MMP2
• MMP9

Mechanisms of action (all sources)

• bacterial cell wall synthesis inhibitor
• mrcA INHIBITOR
• mrcB INHIBITOR
• dacC INHIBITOR
• mrdA INHIBITOR
• ftsI INHIBITOR
• dacA INHIBITOR
• dacB INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PDE4A
• ABCC4
• OPRK1
• HTR1A
• HTR2A
• HTR2B
• HTR3A
• KCNH2
• MAOA
• OPRD1
• OPRM1
• HRH2
• PDE3A
• PDE4D
• PGR
• PTGS1
• SLC6A2
• SLC6A3
• SLC6A4
• HRH3
• HRH1
• ACHE
• HDAC6
• ADORA1
• ADRA1A
• ADRA2A
• ADRA2B
• ADRA2C
• ADRB2
• ALB
• AR
• CHRM1
• CHRM2
• CHRM3
• CNR1
• DRD1
• DRD2
• DRD3
• ESR1
• F2

Drug classes

• Cephalosporin Antibacterial
• Anti-Bacterial Agents
• Anti-Infective Agents

ATC classes

• J01D · OTHER BETA-LACTAM ANTIBACTERIALS
• S01A · ANTIINFECTIVES
• COMBINATIONS OF ANTIBACTERIALS

Cross-references

• PubChem CID: 6321416
• ChEMBL: CHEMBL1095930
• ChEBI: CHEBI:3516
• KEGG: D00914
• RxNorm: 20493
• Wikipedia: Cefuroxime_axetil

Synonyms

• CEFTIN
• cefazine
• altacef
• ceftin
• cefurax
• oraxim
• Cefuroxime 1-acetoxyethyl ester
• Cefurax
• Cefuroxime (as axetil)
• Cepazine
• Cetoxil
• Curocef
• Elobact
• Novador
• Novocef
• Oraxim
• Zinat
• CCI-15641
• NSC-758677
• Ceftin
• Zinnat
• cefuroxime axetil (ep monograph)
• NSC 758677
• Z49QDT0J8Z
• cefuroxime axetil (usp monograph)
• cefuroxime axetil (usp-rs)
• RefChem:56908
• DTXCID702775
• Cefuroxime Axetil for Oral Suspension
• acetoxyethylcefuroxime
• CHEBI:3516
• C20H22N4O10S
• Bioracef
• CXM-AX
• Coliofossim
• Celocid

Reported adverse events

• Stevens-Johnson syndrome
• Seizure
• Eosinophilia
• Nausea
• Rash
• Abdominal pain
• Chills
• Dysuria
• Headache
• Jarisch-Herxheimer reaction
• Pseudomembranous colitis
• Vomiting