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AZOSEMIDE
SynDRA canonical compound SYN0021760 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Primary target(s) | SLC12A1 | SLC12A2 |
| Mechanism of action | electrolyte reabsorption inhibitor |
| Indication | edema |
| Disease area | cardiology |
All known targets
Mechanisms of action (all sources)
- electrolyte reabsorption inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- PDE4D
- HTR2C
- MC3R
- MAPK1
- MAOA
- KCNH2
- HTR3A
- HTR2B
- NPY1R
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HDAC6
- MLNR
- ABL1
- ADORA1
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- TRIM24
- GSK3B
- GLS
- GHSR
- FGFR2
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Diuretics
- Natriuretic Agents
Cross-references
Synonyms
- diurapid
- azosemid
- Azosemida
- Azosemid
- Diart
- Luret
- Azosemidum
- PLE 1053
- Azosemidum [INN-Latin]
- Azosemida [INN-Spanish]
- UNII-MR40VT1L8Z
- Azosemide [USAN:INN:JAN]
- C12H11ClN6O2S2
- EINECS 248-549-7
- SK-110
- BRN 1178491
- MR40VT1L8Z
- 2-chloro-5-(2H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
- CHEBI:31248
- NCGC00181340-01
- 5-(4'-Chloro-5'-sulfamoyl-2'-thenylaminophenyl)-tetrazole
- 2-Chloro-5-(1H-tetrazol-5-yl)-N(sup 4)-2-thenylsulfanilamide
- Benzenesulfonamide, 2-chloro-5-(1H-tetrazol-5-yl)-4-((2-thienylmethyl)
- 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazole
- DTXCID5026910
- 5-(4-chloro-5-sulfamyl-2-thienylaminophenyl)tetrazole
- RefChem:560609
- MFCD00867321
- 2-Chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide
- SK 110
- CAS-27589-33-9
- IWE
- Diart (TN)
- AZOSEMIDE [INN]
- AZOSEMIDE [JAN]
- AZOSEMIDE [MI]
- AZOSEMIDE [USAN]
- AZOSEMIDE [MART.]
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