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PH-797804
SynDRA canonical compound SYN0021679 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | MAPK14 |
|---|
| Mechanism of action | P38 MAPK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- MAPK14 INHIBITOR
- MAP kinase p38 alpha inhibitor
- MAPK11 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ROCK2
- SYK
- STRADA
- AAK1
- PAICS
- PAK6
- PAK4
- PAK2
- OPA1
- PDGFRB
- NUAK2
- NQO2
- NLK
- NEK9
- NEK3
- NEK2
- PASK
- PDXK
- NDUFA13
- PKN2
- PRKAG1
- PRKACB
- PRKACA
- PRKAA1
- PLK4
- PKN3
- PKN1
- PEBP1
- PKMYT1
- PIP4K2C
- PIM1
- PHKG2
- PGRMC1
- PFKP
- NEK1
- NAT10
- PRKCA
- MYLK3
- MAP3K5
- MAP3K6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- PHA-797804
- PH 797804
- PH797804
- 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide
- UNII-SI09I1V827
- UNII-GEL7GRJ3R6
- GEL7GRJ3R6
- CHEMBL1088751
- CHEBI:82715
- SI09I1V827
- 3-{3-Bromo-4-[(2,4-Difluorobenzyl)oxy]-6-Methyl-2-Oxopyridin-1(2h)-Yl}-N,4-Dimethylbenzamide
- 3-Bromo-4-((2,4-difluorobenzyl)oxy)-1-(5-((methylamino)carbonyl)-2-methylphenyl)-6-methylpyridin-2(1H)-one
- 3hll
- KCAJXIDMCNPGHZ-UHFFFAOYSA-N
- RefChem:860493
- DTXCID70129833
- (S)-(-)-PH-797804
- C22H19BrF2N2O3
- Kinome_3761
- MLS006011016
- rac-PH 797804
- GTPL7818
- orb1306903
- orb2283348
- SCHEMBL2015676
- SCHEMBL29351545
- SCHEMBL29527304
- HMS3656N17
- HMS3674G03
- EX-A2344
- IEC02780
- BDBM50314073
- EBC-24083
- NSC785338
- NSC800850
- s2726
- AKOS016007727
- CCG-264986
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