← SynDRA
ROPIVACAINE
SynDRA canonical compound SYN0021461 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN10A | SCN9A |
|---|
| Mechanism of action | sodium channel blocker |
|---|
| Indication | anesthetic |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SCN10A
- SCN9A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN5A
- SCN8A
- SCN11A
- SCN7A
- KCNK3
Mechanisms of action (all sources)
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
- sodium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- NR1I2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- LMNA
- MAOA
- MC3R
- MLNR
- NPY1R
- NR3C1
- HRH1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HRH2
- HDAC6
- ADORA2A
- CCKAR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- Amide Local Anesthetic
ATC classes
- N01B · ANESTHETICS, LOCAL
Cross-references
Synonyms
- NAROPIN
- Naropin
- ROPIVACAINE HYDROCHLORIDE
- (-)-Ropivacaine
- anapeine
- naropeine
- naropine
- S-Ropivacaine
- ropivacaine hydrochloride monohydrate
- ropivacaine hydrochloride
- ropivacaine HCl
- Ropivacaina
- Ropivicaine
- TLC590
- TLC-590
- ROPIVACAINE HCl
- Ropivacaine hydrochloride
- Ropivacaine monohydrochloride
- Naropin (TN)
- Ropivacaine monohydrochloride, (S)-isomer
- 7IO5LYA57N
- (S)-(-)-1-PROPYL-2',6'-PIPECOLOXYLIDINE
- ropivacaine (usp-rs)
- (S)-Ropivacaine
- Ropivacainum
- (-)-1-Propyl-2',6'-pipecoloxylidide
- L-N-n-propylpipecolic acid-2,6-xylidide
- CHEBI:8890
- (S)-(-)-1-propyl-2',6'-pipecoloxylidide
- 1 Propyl 2',6' pipecoloxylidide
- AL-381
- (-)-1-Propyl-2',6'-dimethyl-2-piperidylcarboxyanilid
- LEA 103
- CHEBI:60802
- RefChem:55986
- LEA103
- DTXCID2020187
- N01BB09
Look up ROPIVACAINE in the interactive SynDRA portal →