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THIOPROPERAZINE
SynDRA canonical compound SYN0020761 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRA1A | ADRA1B | DRD1 | DRD2 | HTR1A | HTR2A |
|---|
| Mechanism of action | dopamine receptor antagonist |
|---|
| Indication | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- ADRA1A
- ADRA1B
- DRD1
- DRD3
- HTR1A
- HTR2A
Mechanisms of action (all sources)
- dopamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH1
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB2
- TBXA2R
- KCNH2
- CHRM1
- CHRM2
- HTR2C
- OPRD1
- OPRM1
- OPRK1
- LMNA
- MAOA
- PDE4A
- IDH1
- PDE3A
- SAMHD1
- PDE4D
- PGR
- PTGS1
- SLC6A2
- SLC6A3
- SLC6A4
- SMAD3
- TDP1
- HTR3A
- ACHE
- HTR2B
- HRH3
- ALOX15B
- AR
- ATXN2
- BAZ2B
- CHRM3
- CNR1
- CYP1A2
- CYP2C19
- CYP2C9
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ALR
- SYK
- SMAD2
- SC5A7
- RARA
- NSD2
- MDR1
- KSYK
- IL1B
- IDHC
- GPR151
- GLI3
- ESRRA
- ESR2
- CP3A7
- CP3A4
- CP2D6
- CP1A2
- CASP7
- CASP3
- TSHR
ATC classes
Cross-references
Synonyms
- sulfenazin
- thioperazine
- tioproperazin
- thioproperazine dimesylate
- thioproperazine mesylate
- thioproperazine mesyiate
- thioproperazine mesilate
- Tioproperazina
- Thioperazine
- Thioproperazin
- Sulfenazin
- Tioproperazin
- Cephalmin
- Majeptyl
- Mazeptyl
- Megeptil
- Vontil
- Thiproperazine
- Tioproferazina
- Thioproperazinum [INN-Latin]
- Tioproferazina [INN-Spanish]
- Thioproperazinum
- Thioproperazine [INN]
- N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
- SKF 5883
- RP 7843
- (Thioproperazine)-2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine
- 10H-Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-
- 7843 R.P.
- N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide
- YJ050AQ56X
- CHEBI:59120
- N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide
- 10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-10-(3-(4-methyl-1-piperazinyl)propyl)-
- N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine-2-sulfonamide
- Thioproperazine (INN)
- 2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine
- RP 7843; SKF 5883; Sulfenazin; Thioperazine
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