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CAPECITABINE
SynDRA canonical compound SYN0020552 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TYMS |
|---|
| Mechanism of action | Thymidylate synthase inhibitor |
|---|
| Indication | breast cancer | colorectal cancer |
|---|
| Disease area | oncology |
|---|
All known targets
- TYMS
- Candi TMP1
- DPYD
- CD44
- TERT
- ABCC5
- ABCC11
- CYP19A1
- Tyms
- upp
Mechanisms of action (all sources)
- DNA synthesis inhibitor
- thymidylate synthase inhibitor
- TYMS INHIBITOR
- Candi TMP1 INHIBITOR
- RNA synthesis inhibitor
- DPYD INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- ADORA2A
- HRH1
- HRH2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARG
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HDAC6
- GHSR
- FAAH
- CCKBR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
Drug classes
- Nucleic Acid Synthesis Inhibitors
- Nucleoside Metabolic Inhibitor
- Antimetabolites
- Antimetabolites, Antineoplastic
- Antineoplastic Agents
- Noxae
- Appetite Stimulants
- Central Nervous System Agents
- Central Nervous System Stimulants
- Immunologic Factors
- Immunosuppressive Agents
ATC classes
Cross-references
Synonyms
- XELODA
- Xeloda
- capecitibine
- capecytabine
- capiibine
- captabin
- xeloda
- Capecitabina
- Capecitabine accord
- Capecitabine medac
- Capecitabine sun
- Capecitabine teva
- Capecitibine
- Capecytabine
- Capiibine
- Captabin
- Ecansya
- NSC-759853
- RO 09-1978/000
- RO-09-1978000
- RO-091978000
- Ro-09-1978-000
- Capecitabine component of xeliri capecitibine
- Capecitabine component of xelox
- Ecansya (previously capecitabine krka)
- Capecitabin
- Capecitabinum
- Caxeta
- Xabine
- Capecitabine [USAN]
- R340;R-340
- RG-340
- Ro-09-1978
- Xeloda (TN)
- Ro-09-1978/000
- Xeloda, Captabin, Capecitabine
- Capecitabine (JAN/USAN/INN)
Reported adverse events
- Alopecia
- Arthralgia
- Asthenia
- Constipation
- Cough
- Dermatitis
- Dizziness
- Dyspepsia
- Fatigue
- Headache
- Infection
- Lethargy
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