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LATREPIRDINE
SynDRA canonical compound SYN0020347 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | HTR6 |
|---|
| Mechanism of action | Glutamate receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Glutamate receptor antagonist
- HTR6 INHIBITOR
- HRH1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1D
- HTR2B
- DRD3
- DRD2
- HTR1E
- HTR7
- HTR5A
- SIGMAR1
- BCHE
- HRH2
- HTR2C
- HTR2A
- HTR1B
- ADRA2C
- ADRA2B
- ADRA2A
- ADRA1D
- ADRA1B
- ADRA1A
- DRD4
- NFE2L2
- HTR3A
- NEIL1
- NEIL2
- ACHE
- OPRD1
- OPRK1
- PIN1
- S1PR1
- SLC6A2
- SLC6A4
- SMUG1
- TDG
- TMEM97
- TP53
- OPRM1
- GPR35
- HTR1A
- HRH3
- ADRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- CP2C9
- CP2D6
- CP3A7
- GAMT
- GNMT
- HNMT
- NNMT
- NSD2
- PNMT
Cross-references
Synonyms
- Latrepirdina
- Dimebolin
- Dimebon
- Pf-01913539
- DIMEBOLIN
- Dimebone
- Dimeboline
- Preparation 84
- UNII-OD9237K1Z6
- C21H25N3
- BRN 0622478
- CHEMBL589390
- JNODQFNWMXFMEV-UHFFFAOYSA-N
- OD9237K1Z6
- 2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole
- 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
- PF-01913539
- 2,8-Dimethyl-5-[2-(6-methyl-pyridin-3-yl)-ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
- SMR001317776
- Latrepirdine [USAN]
- Latrepirdine [USAN:INN]
- 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole
- 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
- DIMEBOLIN [MI]
- Dimebolin-Dihydrochloride
- Latrepirdine (USAN/INN)
- LATREPIRDINE [INN]
- LATREPIRDINE [MART.]
- MLS002264475
- MLS006013366
- LATREPIRDINE [WHO-DD]
- SCHEMBL292354
- LATREPIRDINE HYDROCHLORIDE
- CHEBI:92976
- DTXSID20189705
- BCPP000257
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