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TERBUTALINE
SynDRA canonical compound SYN0020318 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRB2 |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
| Indication | bronchitis | bronchospasm | emphysema |
|---|
| Disease area | pulmonary |
|---|
All known targets
- ADRB2
- ADRB1
- BCHE
- CYP2D6
- ACHE
- Bche
- Ache
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- ADRB2 AGONIST
- Beta-2 adrenergic receptor agonist
- ADRB1 PARTIAL AGONIST
- ADRB2 PARTIAL AGONIST
- BCHE INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ACHE
- OPRK1
- NR3C1
- NR1I2
- NPY2R
- NPY1R
- NFE2L2
- MPHOSPH8
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4E
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH3
- HRH2
- OPRD1
- OPRM1
- HMGCR
- PDE5A
- TDP1
- TBXAS1
- TBXA2R
- TARDBP
- TACR2
- TACR1
- SMN1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2D6
- CREB1
- ESRRA
- GNRHR
- GRK2
- SC5A7
- TSHR
Drug classes
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic beta-2 Receptor Agonists
- Adrenergic beta-Agonists
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Reproductive Control Agents
- Respiratory System Agents
- Sympathomimetics
- Tocolytic Agents
ATC classes
- R03C · ADRENERGICS FOR SYSTEMIC USE
- R03A · ADRENERGICS, INHALANTS
Cross-references
Synonyms
- BRETHAIRE
- BRETHINE
- BRICANYL
- TERBUTALINE SULFATE
- bricaril
- terbutalin
- brican
- terbutaline sulfate
- terbutaline hemisulfate
- Terbutalina
- Asthmasian
- Terbutalin
- Brethaire
- Brethine
- Brican
- Bricanyl
- Bricar
- Bricaril
- Bricyn
- Terbutalino
- Terbutalinum
- Terbutalina [DCIT]
- Terbutaline sulfate
- KWD-2019
- Asthmasian (TN)
- Brethaire (TN)
- Brethine (TN)
- Bricanyl (TN)
- Terbutaline (INN)
- Terbutaline [INN:BAN]
- Terbutalino [INN-Spanish]
- Terbutalinum [INN-Latin]
- (+-)-Terbutaline
- 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol
- TERBUTALINE HEMISULFATE
- 5-(2-(tert-Butylamino)-1-hydroxyethyl)benzene-1,3-diol
- Aerodur; Brican; Bricar
- N8ONU3L3PG
Reported adverse events
- Headache
- Nausea
- Palpitations
- Tachycardia
- Tremor
- Anxiety
- Somnolence
- Asthenia
- Dizziness
- Extrasystoles
- Insomnia
- Nervousness
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