← SynDRA
SOTRASTAURIN
SynDRA canonical compound SYN0020314 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | PRKCQ |
|---|
| Mechanism of action | PKC inhibitor |
|---|
All known targets
- PRKCA
- PRKCB
- PRKCQ
- PRKCD
- PRKCE
- PRKCH
- PRKCG
- PRKCI
- PRKCZ
- PRKD1
- PRKD3
Mechanisms of action (all sources)
- PKC inhibitor
- PRKD3 INHIBITOR
- Protein kinase C (PKC) inhibitor
- PRKCI INHIBITOR
- PRKCA INHIBITOR
- PRKCG INHIBITOR
- PRKCD INHIBITOR
- PRKCB INHIBITOR
- PRKCZ INHIBITOR
- PRKCE INHIBITOR
- PRKCH INHIBITOR
- PRKD1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CDK1
- AXL
- RPS6KA6
- SYK
- MINK1
- KDR
- JAK3
- FER
- STK3
- JAK1
- MST1R
- CLK2
- FLT4
- CILK1
- FYN
- SLK
- GTPBP4
- CDK2
- GSK3B
- GSK3A
- CDK5
- PDK1
- TAOK1
- AKT1
- MARK3
- ABL1
- PIM2
- PKN1
- AKT2
- CYP3A4
- PIM1
- ERBB2
- PKN2
- TNIK
- EGFR
- MAP4K4
- PTK2
- PAK1
- PKMYT1
- NTRK3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AAPK1
- KS6B1
- VGFR2
- PGFRB
- NSD2
- MP2K1
- M4K5
- M4K4
- KSYK
- KS6A3
- CCNA1
- KGP1
- KCC2G
- KCC2D
- KCC2B
- KCC2A
- KCC1D
- CCNA2
- VGFR3
Cross-references
Synonyms
- Sotrastaurine
- Sotrastaurina
- AEB-071
- AEB071
- NVP-AEB071
- AEB 071
- sotrastaurina
- sotrastaurine
- sotrastaurinum
- 7I279E1NZ8
- CHEBI:90531
- RefChem:931988
- Sotrastaurin (AEB071)
- C25H22N6O2
- Sotrastaurin [USAN]
- Sotrastaurin [USAN:INN]
- Sotrastaurin?
- UNII-7I279E1NZ8
- MFCD16038049
- Kinome_2717
- Sotrastaurin (Standard)
- Sotrastaurin (USAN/INN)
- SOTRASTAURIN [INN]
- NVP-AEB-071
- SOTRASTAURIN [WHO-DD]
- GTPL7946
- orb1300910
- SCHEMBL2500835
- SCHEMBL26184899
- SCHEMBL29364923
- SCHEMBL29526075
- BDBM33971
- OAVGBZOFDPFGPJ-UHFFFAOYSA-N
- GLXC-90304
- HMS3656D10
- HMS3673M05
- HMS3744G03
- EX-A2802
Look up SOTRASTAURIN in the interactive SynDRA portal →