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ESTRAMUSTINE PHOSPHATE
SynDRA canonical compound SYN0020302 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | MAP2 |
|---|
| Mechanism of action | Estrogen receptor agonist |
|---|
| Indication | prostate cancer |
|---|
| Disease area | oncology |
|---|
All known targets
- ESR2
- ESR1
- MAP1A
- MAP2
- INPPL1
- PTPN1
- PTPN11
- PTPN6
Mechanisms of action (all sources)
- DNA inhibitor
- DNA alkylating agent
- microtubule inhibitor
- DNA synthesis inhibitor
- ESR1 AGONIST
- ESR2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA3
- ACHE
- HTR2B
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- HTR1A
- HRH3
- HDAC6
- F2
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2A
- ADRA1A
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALOX12
- ANDR
- GPX4
- LOX12
- TP53
Drug classes
- Alkylating Agents
- Antineoplastic Agents
- Antineoplastic Agents, Alkylating
- Antineoplastic Agents, Hormonal
- Noxae
- Alkylating Activity
- Alkylating Drug
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- EMCYT
- Emcyt
- emcyt
- estramustine phosphate sodium
- Estramustine 17-(dihydrogen phosphate)
- Ls-299
- NSC-89199
- Estracyt
- estramustine-phosphate
- estramustine.phosphate
- Emcyt (free acid)
- Leo 299
- LS-299
- NSC 89199
- CHEMBL1756
- MUZ9585Y7B
- CHEBI:68643
- Estradiol, 3-(bis(2-chloroethyl)carbamate) dihydrogen phosphate
- Estradiol, 3-[bis(2-chloroethyl)carbamate] dihydrogen phosphate
- UNII-MUZ9585Y7B
- NCGC00184995-01
- NSC89199
- EINECS 225-512-3
- BRN 1898199
- SCHEMBL234749
- DTXSID7048667
- ZINC3938713
- Tox21_113033
- BDBM50333645
- HY-13627A
- AKOS025401368
- AC-1305
- DB14674
- ESTRAMUSTINE PHOSPHATE [WHO-DD]
- NCGC00484900-01
- CAS-4891-15-0
- CS-0133861
- AB01273936-01
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