← SynDRA

COTININE

SynDRA canonical compound SYN0020301 — structure-anchored drug synonym record

All known targets

• CHRNA2

Mechanisms of action (all sources)

• nicotine metabolite

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ACHE
• ADORA1
• HRH1
• HRH2
• HRH3
• HTR1A
• HTR1D
• HTR2A
• HTR2C
• HTR3A
• HTR4
• HTR7
• KCNH2
• LTB4R
• NPY2R
• OPRM1
• PDE5A
• PRKCA
• RGS4
• SAMHD1
• SIGMAR1
• SLC6A3
• SLC6A4
• SLCO1B1
• SLCO1B3
• TACR1
• TBXA2R
• HDAC6
• GALC
• GABRA1
• CHRM1
• ADORA2A
• ADRA1A
• ADRA1B
• ADRA2A
• ADRA2B
• ADRA2C
• ADRB1
• ADRB2
• AGTR1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• MDR1

Drug classes

• Indicators and Reagents

Cross-references

• PubChem CID: 854019
• ChEMBL: CHEMBL578211
• ChEBI: CHEBI:68641
• KEGG: D03596
• PDB: U5H
• Wikipedia: Cotinine
• TTD: D0TY5N
• LINCS BRD: BRD-K94144010

Synonyms

• (-)-Cotinine
• (S)-Cotinine
• cotinine fumarate
• Cotinina
• Nicotine related compound c
• Cotininum
• (S)-(-)-Cotinine
• (5S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
• Cotinine (-)
• UNII-K5161X06LL
• (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
• 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)-
• CHEBI:68641
• (S)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone
• UIKROCXWUNQSPJ-VIFPVBQESA-N
• K5161X06LL
• Cotinine [INN]
• MFCD00077696
• Cotininum [INN-Latin]
• Cotinina [INN-Spanish]
• S(-)-1-Methyl-5-(3-pyridyl)-2-pyrrolidone
• (5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one
• S-(-)-Cotinine
• n-methyl-2-(3-pyridyl)-5-pyrrolidone
• 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-
• DTXCID9027576
• Scotine
• RefChem:128208
• 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
• 1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
• (S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
• (5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one
• (5~{S})-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one
• BRD4010
• Nicotine EP Impurity C
• BRD-4010
• SMR000449278
• S-(-)-Cotinine (1.0 mg/mL in Methanol)