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DYPHYLLINE
SynDRA canonical compound SYN0020296 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | PDE4D |
|---|
| Mechanism of action | Adenosine receptor antagonist |
|---|
| Indication | asthma | bronchitis | emphysema |
|---|
| Disease area | pulmonary |
|---|
All known targets
- PDE4A
- PDE4B
- PDE3A
- PDE4C
- PDE4D
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- Adenosine receptor antagonist
- PDE4A INHIBITOR
- Phosphodiesterase 4 inhibitor
- PDE4D INHIBITOR
- PDE4B INHIBITOR
- PDE4C INHIBITOR
- PDE3A INHIBITOR
- Phosphodiesterase 3A inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- GMNN
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- NR3C1
- OPRD1
- OPRK1
- SIGMAR1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SMN1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SAMHD1
Drug classes
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Phosphodiesterase Inhibitors
- Respiratory System Agents
- Vasodilator Agents
ATC classes
- R03D · OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Cross-references
Synonyms
- DILOR
- DILOR-400
- LUFYLLIN
- NEOTHYLLINE
- diprophylline
- aristophyllin
- corphyllin
- diphyllin
- diphylline
- diprophyllin
- glyphyllin
- glyphylline
- hidroxiteofillina
- neophyllin
- neutrafillina
- neutraphyllin
- neutraphylline
- neutroxantina
- protheophylline
- propyphyllin
- synthophylline
- Diprophylline
- Diprofilina
- Dyphilline
- NSC-14305
- Dilor
- Dilor-400
- Lufyllin
- Neothylline
- Aristophyllin
- Asthmolysin
- Astmamasit
- Astrophyllin
- Circain
- Circair
- Coronal
- Coronarin
- Corphyllin
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