← SynDRA
OBETICHOLIC ACID
SynDRA canonical compound SYN0020188 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR1H4 |
|---|
| Mechanism of action | FXR agonist |
|---|
All known targets
Mechanisms of action (all sources)
- NR1H4 AGONIST
- Bile acid receptor FXR agonist
- NR1H4 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- DGAT2
- ABL1
- MPG
- NR3C1
- NR2E1
- NR2C1
- NR1I2
- NPY1R
- NEIL2
- NEIL1
- MUTYH
- MLNR
- NR5A1
- MC3R
- MBD4
- MAPK1
- MAOA
- KDR
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- NR4A1
- NTHL1
- HTR1A
- OGG1
- TRIM24
- TDG
- TBXA2R
- SMUG1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SCN5A
- RXRA
- PTGS2
- PTGS1
- PGR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Farnesoid X Receptor Agonists
- Farnesoid X Receptor Agonist
ATC classes
Cross-references
Synonyms
- OCALIVA
- Ocaliva
- ocaliva
- 6-ECDCA
- 6ECDCA
- INT-747
- Acide obeticholique
- Acido obeticolico
- 6-ecdca
- 6-ethylchenodeoxycholic acid
- DSP-1747
- INT747
- OCA
- 6-Et CDCA
- 6-Ethylchenodeoxycholic acid
- INT 747
- 6-alpha-ethylchenodeoxycholic acid
- 6-Ethyl-CDCA
- 6alpha-ethylchenodeoxycholic acid
- acido obeticolico
- acide obeticholique
- DSP1747
- CHEBI:43602
- ObeticholicAcid
- acidum obeticholicum
- RefChem:57128
- A05AA04
- DTXCID60119162
- 6-ETHYL-CHENODEOXYCHOLIC ACID
- Obetichloic acid
- 6alpha-Ethyl-chenodeoxycholic acid
- MFCD16621104
- UNII-0462Z4S4OZ
- Obeticholic acid [USAN]
- Obeticholic acid [USAN:INN]
- 1osv
Look up OBETICHOLIC ACID in the interactive SynDRA portal →