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GLUTAMIC ACID
SynDRA canonical compound SYN0020175 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | GRM8 |
|---|
| Mechanism of action | Glutamate receptor agonist |
|---|
All known targets
- GRM7
- GRM8
- GRM3
- GRIK4
- GRIA1
- GRM4
- GLUD2
- GLUD1
- GRIA2
- GRIA3
- GRIA4
- GRIK1
Mechanisms of action (all sources)
- Glutamate receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA1
- ACHE
- PIN1
- KCNH2
- KDM4A
- KDR
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- PTGS1
- HTR1A
- RAPGEF3
- RGS4
- SLC16A10
- SLC6A2
- SLC6A3
- SLC6A4
- SLC7A5
- TBXA2R
- HTR2B
- HRH3
- ADRA1A
- CYP1A2
- ADRA2A
- ADRB2
- AR
- ATAD5
- BAZ2B
- CA2
- CHRM1
- CHRM2
- CYP2C19
- HDAC6
- CYP2C9
- CYP2D6
- CYP3A4
- DRD1
- DRD3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
ATC classes
- A09A · DIGESTIVES, INCL. ENZYMES
Cross-references
Synonyms
- glutamate
- L-Glutamic acid
- glutaminic acid
- glutaminol
- glutamic acid hydrochloride
- glutamic acid HCl
- Acide glutamique
- Acido glutamico
- L-glutamic acid
- Glutamic acid, l-
- Glutamidex
- L-2-amino-pentanedioic acid
- L-alpha-aminoglutaric acid
- L-glutamate
- E-620
- E620
- FEMA NO. 3285
- INS NO.620
- INS-620
- NSC-143503
- L-Glutamic Acid
- Aciglut
- Glu
- Glusate
- Glut
- Glutacid
- Glutamicol
- Glutaminol
- Glutaton
- Gulutamine
- Acidum glutamicum
- Acidum glutaminicum
- Glutamic acid polymer
- Glutaminic acid
- E 620
- A-Aminoglutaric acid
- A-Glutamic acid
- Acide glutamique [INN-French]
Reported adverse events
- Local reaction
- Alkalosis
- Electrolyte imbalance
- Hypersensitivity
- Metabolic acidosis
- Pulmonary embolism
- Refeeding syndrome
- Sepsis
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