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BX-795
SynDRA canonical compound SYN0020051 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PDPK1 |
|---|
| Mechanism of action | IKK inhibitor |
|---|
All known targets
- PDPK1
- KDR
- CHEK1
- CDK2
- GSK3B
- PDK1
- TBK1
- IKBKE
- Fung ypkA
- PRKACA
- PRKACB
- PRKACG
Mechanisms of action (all sources)
- IKK inhibitor
- PDPK1 INHIBITOR
- AURKB INHIBITOR
- CHEK1 INHIBITOR
- CDK2 INHIBITOR
- GSK3B INHIBITOR
- IKBKE INHIBITOR
- KDR INHIBITOR
- PRKAR1A INHIBITOR
- PRKAR1B INHIBITOR
- PRKAR2A INHIBITOR
- PRKAR2B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MKNK2
- BRSK2
- ROCK2
- NUAK1
- PKN2
- MKNK1
- CHEK2
- CGAS
- SGK1
- CAMKK2
- PRKD1
- MELK
- MAP2K1
- MARK3
- MAPK15
- YES1
- SYK
- ULK2
- AURKC
- ULK1
- PDGFRA
- NEK9
- NTRK1
- NTRK2
- NTRK3
- PAK2
- PIM3
- PIM1
- PIM2
- PDGFRB
- PAK3
- PHKG2
- PAK4
- PAK5
- NEK6
- PAK6
- PHKG1
- PASK
- NEK7
- AAK1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ATXN2
- CCNA1
- CCNA2
- KSYK
- NSD2
- NTM1A
- NTMT1
- VGFR2
Cross-references
Synonyms
- BX 795
- BX795
- RefChem:1091125
- DTXCID40386012
- MFCD12546134
- C23H26IN7O2S
- BX7
- MLS006011190
- GTPL8006
- orb1307362
- SCHEMBL3865995
- SCHEMBL29382898
- SCHEMBL29850938
- BDBM17051
- CHEBI:91439
- EX-A262
- GLXC-04290
- HMS3244G15
- HMS3244G16
- HMS3244H15
- HMS3651A07
- HMS3672K09
- BX795?
- s1274
- AKOS016369934
- CCG-264884
- CS-0259
- SB13079
- SDCCGSBI-0645948.P001
- NCGC00250386-01
- NCGC00250386-02
- NCGC00250386-09
- NCGC00250386-12
- AC-32825
- AS-16196
- HY-10514
- SMR004702959
- BX-795, 3
- B9200
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