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GAMBOGIC ACID
SynDRA canonical compound SYN0019638 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | BCL2 | TOP2A |
|---|
| Mechanism of action | caspase activator |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- BCL2A1
- IKBKB
- TXN
- SPTSSB
- RGS17
- PTPN1
- BCL2L1
- MCL1
- TXN2
- HSP90AA1
- BCL2L2
- BCL2L10
- MAPK1
- MAPK3
- HDAC6
- NFKBIA
- NTRK1
- NTRK2
- NTRK3
- GNAO1
- CDC37
- SLCO1B1
- SLCO1B3
- TP53
- MDM2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- (-)-Gambogic Acid
- R-gambogic acid
- beta-Guttiferin
- 8N585K83U2
- 1,6-dihydroxy-3,5-dimethoxy-xanthen-9-one
- RefChem:142249
- DTXCID101514922
- MFCD16878985
- Cambogic acid
- B''-Guttiferin
- C38H44O8
- .beta.-Guttiferin
- |A-Guttilactone
- GAMBOGICACID
- UNII-8N585K83U2
- |?-Guttilactone
- GEZHEQNLKAOMCA-RRZNCOCZSA-N
- 2(R)-gambogic acid
- Gambogic Acid (Standard)
- GAMBOGIC ACID [MI]
- SCHEMBL16160279
- SCHEMBL29351509
- HY-N0087R
- GLXC-02792
- HY-N0087
- BDBM50366237
- s2448
- AKOS024463359
- CCG-270284
- CS-1456
- EBC-369046
- FG42759
- AC-34804
- BP-22199
- Gambogic acid, >=95% (HPLC), powder
- SY074643
- H10129
- F818128
- (-)-gambogic acid
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