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TYRPHOSTIN AG 879
SynDRA canonical compound SYN0019614 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ERBB2 | KDR | NTRK1 |
|---|
| Mechanism of action | tyrosine kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- tyrosine kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- ALOX15
- KMT2A
- LMNA
- MAPT
- MPHOSPH8
- MTOR
- NFE2L2
- NFKB1
- PIN1
- PMP22
- POLI
- RAB9A
- RECQL
- RGS4
- SMN1
- SNCA
- TDP1
- THPO
- TSHR
- USP1
- KDM4E
- KCNH2
- HSD17B10
- CYP1A2
- ALOX15B
- APEX1
- APP
- ARSA
- ATAD5
- ATXN2
- BLM
- CBX1
- CYP2C19
- HPGD
- CYP2C9
- CYP2D6
- CYP3A4
- DRD1
- EHMT2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- HNMT
- TPO
- STK33
- PNMT
- NPR2
- NPR1
- NNMT
- IFNG
- GNMT
- CP1A2
- GLSK
- GEMI
- GAMT
- ESRRA
- CP3A4
- CP2CJ
- CP2C9
- YAP1
Cross-references
Synonyms
- RefChem:900834
- tyrphostin-AG-879
- AG 879
- AG879
- MFCD00236450
- C18H24N2OS
- alpha-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide
- TyrphostinAG879
- tyrphostin AG879
- BiomolKI_000028
- Lopac-T-2067
- BiomolKI2_000036
- Lopac0_001175
- BMK1-D4
- BSPBio_001398
- SCHEMBL607701
- GTPL4863
- orb1300532
- BCBcMAP01_000075
- CHEBI:93041
- XRZYELWZLNAXGE-KPKJPENVSA-N
- GLXC-07087
- HMS1361F20
- HMS1791F20
- HMS1989F20
- HMS3263L11
- HMS3402F20
- CS-D0050
- EX-A1893
- Tyrphostin AG 879 (AG 879)
- Tox21_501175
- AG879?
- BDBM50468261
- EI-258
- s2816
- AKOS024256594
- CCG-100632
- LP01175
- SDCCGSBI-0051142.P002
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