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VINORELBINE
SynDRA canonical compound SYN0019593 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TUBB |
|---|
| Mechanism of action | Tubulin inhibitor |
|---|
| Indication | non-small cell lung cancer (NSCLC) |
|---|
| Disease area | oncology |
|---|
All known targets
- TUBB
- TUBB1
- TUBB6
- TUBB4B
- TUBB4A
- TUBB3
- TUBB2B
- TUBB2A
- TUBB8
- TUBA4A
- TUBA3E
- TUBA3C
Mechanisms of action (all sources)
- microtubule inhibitor
- TUBB4B INHIBITOR
- TUBB1 INHIBITOR
- TUBA3C INHIBITOR
- TUBA4A INHIBITOR
- TUBB3 INHIBITOR
- TUBA1A INHIBITOR
- TUBB4A INHIBITOR
- TUBB8 INHIBITOR
- TUBB INHIBITOR
- TUBA1B INHIBITOR
- TUBA1C INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ESR2
- ESR1
- OPRM1
- KDR
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- ABCB1
- NPY1R
- KAT2A
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- MMP9
- NPY2R
- HDAC6
- PTPRC
- VDR
- TDP1
- TBXAS1
- TBXA2R
- TACR1
- SMAD3
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- PTGS2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- NF2L2
- TP53
- SYK
- SMAD2
- RARA
- PRGR
- NSD2
- NR1I2
- NR1H4
- MDR1
- ATAD5
- KSYK
- JUN
- IFNG
- GLI3
- ESRRA
- CP3A7
- CP3A4
- ATXN2
- YAP1
Drug classes
- Antimitotic Agents
- Antineoplastic Agents
- Antineoplastic Agents, Phytogenic
- Tubulin Modulators
- Vinca Alkaloid
ATC classes
- L01C · PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
Cross-references
Synonyms
- NAVELBINE
- Navelbine
- VINORELBINE TARTRATE
- vinorelbin ditartrate
- noranhydrovinblastine tartrate
- navelbin
- navelbine base
- 5'-anhydrovinblastine
- vinorelbine tartrate
- vinorelbine ditartrate
- navelbine
- vinorelbine base
- Vinorelbina
- Navelbin
- Vinorelbine base
- NSC-760087
- Eunades
- Exelbine
- NVB
- Vinorelbin
- Vinorelbinum
- Navelbine base
- Vinorelbina [Spanish]
- Vinorelbine Ditartarate
- Vinorelbine ditartrate
- Vinorelbine tartrate
- Vinorelbinum [Latin]
- KW-2307
- KW 2307 base
- ANX-530
- Navelbine (TN)
- SDP-012
- Vinorelbine (INN)
- Vinorelbine [INN:BAN]
- Aspidospermidine-3-carboxylic acid
- Nor-5'-anhydrovinblastine
- CHEBI:480999
- Q6C979R91Y
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