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MK-7246
SynDRA canonical compound SYN0019418 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PTGDR2 |
|---|
| Mechanism of action | CRTH receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- PTGDR2 ANTAGONIST
- G protein-coupled receptor 44 antagonist
- CRTH receptor antagonist
- PTGDR2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- GABRA1
- CYP2C9
- TBXA2R
- SLC6A3
- DRD2
- PTGDR
- CYP3A4
- ADRA1D
- AAK1
- PAK5
- PAK6
- PDGFRA
- PDGFRB
- PDPK1
- PHKA2
- PHKG1
- PI4KB
- PAK4
- PAK2
- PAK3
- PIK3C2G
- PAK1
- OXSR1
- OPRM1
- OPRK1
- OGG1
- NUAK2
- NUAK1
- NTRK3
- NTRK2
- NTRK1
- PIK3C2B
- PIK3CB
- PIK3C3
- PIK3CA
- PRKACB
- PRKACA
- PRKAA2
- PRKAA1
- PNCK
Cross-references
Synonyms
- 2-[(7R)-7-(N-METHYL4-FLUOROBENZENESULFONAMIDO)-6H,7H,8H,9H-PYRIDO[1,2-A]INDOL-10-YL]ACETIC ACID
- CRTH2 ANTAGONIST
- CRTH2_ANTAGONIST
- MK7246
- IDDBCP261213
- IDDBCP271467
- X0LHZ71TLK
- RefChem:159212
- CRTH2 antagonist
- MFCD22741619
- C21H21FN2O4S
- MK-7246-d3
- UNII-X0LHZ71TLK
- orb1679063
- SCHEMBL2186905
- SCHEMBL29486331
- GLXC-15109
- EX-A1915
- TYB91862
- BDBM50296980
- TQ0051
- AKOS027321599
- PB37255
- AC-36247
- AS-74694
- HY-15853
- CS-0009391
- F545906
- 2-[(7R)-7-(N-methyl4-fluorobenzenesulfonamido)-
- 6H,7H,8H,9H-pyrido[1,2-a]indol-10-yl]acetic acid
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