PARBENDAZOLE

SynDRA canonical compound SYN0019050 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	TUBB
Mechanism of action	Tubulin inhibitor

All known targets

TUBB

Mechanisms of action (all sources)

microtubule inhibitor
tubulin polymerization inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

CYP1A2
CYP2C19
CYP2C9
CYP2D6
CYP3A4
GALC
GMNN
HDAC6
HIF1A
LMNA
SAMHD1
SLC2A1
TDP1
TSHR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

Drug classes

Antinematodal Agents

Cross-references

PubChem CID: 26596
ChEMBL: CHEMBL528271
DrugBank: DB20965
ChEBI: 94267
KEGG: D05365
PDB: H1C
LINCS BRD: BRD-K02407574

Synonyms

Parbendazol
NSC-256420
SK&F-29044
TCMDC-131798
Helmatac
Methyl (5-butyl-1H-benzo[d]imidazol-2-yl)carbamate
Worm Guard
Verminum
SKF-29044
Helatac
PBDZ
METHYL 5-BUTYL-2-BENZIMIDAZOLECARBAMATE
Carbamic acid, (5-butyl-1H-benzimidazol-2-yl)-, methyl ester
methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate
Parbendazole free base
5-Butyl-2-(carbomethoxyamino)benzimidazole
N4X8WVX2UG
5-Butyl-2-benzimidazolecarbamic acid methyl ester
NSC 256420
14255-87-9 (free base)
NCGC00016706-01
CAS-14255-87-9
Methyl (5-butyl-1H-benzimidazol-2-yl)carbamate
Methyl 5-butyl-1H-benzo[d]imidazol-2-ylcarbamate
methyl ~{N}-(5-butyl-1~{H}-benzimidazol-2-yl)carbamate
Parbendazolum
N-(6-Butyl-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester
Parbendazol [INN-Spanish]
Parbendazolum [INN-Latin]
EINECS 238-133-3
UNII-N4X8WVX2UG
Parbendazole [USAN:INN:BAN]
2-Benzimidazolecarbamic acid, 5-butyl-, methyl ester
(4-Butyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
N-(Butyl-5, benzimidazolyl)-2, carbamate de methyle [French]
Methyl 5(6)-butyl-2-benzimidazolecarbamate
Prestwick0_001110
Prestwick1_001110

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