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BRUCINE
SynDRA canonical compound SYN0018995 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CHRM1 | CHRM2 | CHRM3 | CHRM4 | CHRM5 |
|---|
| Mechanism of action | glycine receptor antagonist |
|---|
All known targets
- CHRM3
- CHRM1
- CHRM2
- CHRM4
- CHRM5
Mechanisms of action (all sources)
- glycine receptor antagonist
- CHRM3 MODULATOR (ALLOSTERIC MODULATOR)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TAS2R10
- APEX1
- GMNN
- HDAC6
- SLCO1B1
- SMN1
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ACM2
- ACM3
- ACM4
- ACM5
- ANDR
- NR1I2
Drug classes
- Adjuvants, Immunologic
- Analgesics
- Indicators and Reagents
Cross-references
Synonyms
- 10,11-dimethoxystrychnine
- 2,3-dimethoxystrychnine
- Brucinum
- NSC-757797
- 10,11-dimethoxy strychnine
- 2,3-Dimethoxystrychnine
- (-)-Brucine
- 2,3-Dimethoxystrychnidin-10-one
- Bruzin
- l-Brucine
- Brucine alkaloid
- Strychnidin-10-one, 2,3-dimethoxy-
- Brucina
- 2,3-Dimethoxy-strychnine
- 6NG17YCK6H
- Strychnine, 2,3-dimethoxy-
- Dimethoxy strychnine
- NSC 757797
- DTXCID204662
- dimethoxystrychnine
- RefChem:917651
- Brucine, Anhydrous
- C23H26N2O4
- RCRA waste number P018
- Brucine Anhydrous
- Brucin [German]
- Brucina [Italian]
- CAS-357-57-3
- SMR000112281
- UNII-6NG17YCK6H
- CCRIS 4754
- HSDB 307
- anhydrous brucine
- Bisdesmethylbrucin
- Brucine CRS
- UN 1570
- NCGC00094861-01
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