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SNS-314
SynDRA canonical compound SYN0018868 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | AURKB |
|---|
| Mechanism of action | Aurora kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- aurora kinase inhibitor
- AURKB INHIBITOR
- Serine/threonine-protein kinase Aurora inhibitor
- AURKC INHIBITOR
- AURKA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DDR2
- NTRK1
- RAF1
- CSF1R
- NTRK2
- AXL
- FLT4
- NQO2
- PAK1
- PDGFRB
- NEK7
- PDGFRA
- PBK
- PAK4
- PAK2
- NEK9
- NLK
- PAICS
- OPA1
- PDPK1
- NUAK2
- NTRK3
- OLA1
- PDXK
- NEK3
- PKN1
- PRKACB
- PRKACA
- PRKAA1
- PLK4
- PLK3
- PLK1
- PKN3
- PKN2
- PKMYT1
- PEBP1
- PIP4K2C
- PIP4K2A
- PIM3
- PIM2
Cross-references
Synonyms
- SN-314
- SNS314
- RefChem:183485
- DTXCID9069760
- Aurora Kinase Inhibitor SNS-314
- UNII-802IFJ0Z8X
- Kinome_3712
- C18H15ClN6OS2
- MFCD16619388
- GTPL9397
- orb1705147
- SCHEMBL3415843
- SCHEMBL29399273
- SCHEMBL30405811
- SNS 314 [WHO-DD]
- BDBM26326
- CHEBI:94720
- EX-A181
- GLXC-03531
- HMS3244O17
- HMS3244O18
- HMS3244P17
- NSC758250
- NSC800886
- s8699
- AKOS025404950
- CCG-269017
- NSC-758250
- NSC-800886
- SB16660
- SDCCGSBI-0654350.P001
- compound 21 [PMID: 18678489]
- NCGC00242482-01
- NCGC00242482-08
- NCGC00242482-11
- AK2
- AS-16236
- DB-059388
Look up SNS-314 in the interactive SynDRA portal →