← SynDRA

ALPHA-KETOGLUTARIC ACID

SynDRA canonical compound SYN0018866 — structure-anchored drug synonym record

All known targets

• OXGR1

Mechanisms of action (all sources)

• OXGR1 FULL AGONIST
• OXGR1 AGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• EGLN1
• OR51E2
• SLC13A3
• ABCB1
• AR
• EGLN2
• EGLN3
• HDAC6
• HIF1AN
• MAPK1
• NFE2L2
• P4HA1
• SLC22A5
• SLC22A6
• SLC22A7
• SLC22A8

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2D6

Cross-references

• PubChem CID: 51
• ChEMBL: CHEMBL1686
• DrugBank: DB08845
• ChEBI: 30915
• KEGG: C00026
• RxNorm: 17511
• PDB: 2OG
• Wikipedia: Α-Ketoglutaric acid
• TTD: D09KQZ

Synonyms

• 2-ketoglutarate
• 2-oxoglutarate
• alpha-ketoglutarate
• 2-ketoglutaric acid
• oxoglutarate
• Oxoglurate
• 2-Oxopentanedioic acid
• 2-Oxoglutaric Acid
• alpha ketoglutaric acid
• 2 Oxoglutarate
• Oxoglutaric acid
• a-ketoglutaric acid
• 2-Oxo-1,5-pentanedioic acid
• Pentanedioic acid, 2-oxo-
• Alphaketoglutaric acid
• oxogluric acid
• Glutaric acid, 2-oxo-
• Glutaric acid, alpha keto
• ketoglutaric acid
• NSC 17391
• 8ID597Z82X
• A-KETOGLUTARICUM ACIDUM
• DTXCID3013179
• CHEBI:30915
• hydron;2-oxopentanedioate
• RefChem:555767
• Oxoglutarate
• alpha-Oxoglutaric acid
• Alpha-Ketoglutarate
• Pentanedioic acid, oxo-
• Bis(L-arginin)-2-oxoglutarat
• Oxoglurate [INN]
• MFCD00004165
• .alpha.-Ketoglutaric acid
• AI3-26938
• 2-oxo-pentanedioic acid
• alpha-keto-Glutaric acid
• NSC17391