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CARBIMAZOLE
SynDRA canonical compound SYN0018829 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | TPO |
|---|
| Mechanism of action | Anti-thyroid agent |
|---|
| Indication | hyperthyroidism |
|---|
| Disease area | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
- TPO INHIBITOR
- Thyroid peroxidase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- HDAC6
- NR1I2
- NR3C1
- OPRD1
- SIGMAR1
- USP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antithyroid Agents
- Hormone Antagonists
- Anti-thyroid agent
- antithyroid agent
ATC classes
- H03B · ANTITHYROID PREPARATIONS
Cross-references
Synonyms
- athyromazole
- carbethoxymethimazole
- carbimazol
- neomercazole
- Carbimazol
- Carbimazol henning
- NSC-758966
- Neo-mercazole 20
- Neo-mercazole 5
- Athyromazole
- Atirozidina
- Basolest
- Carbethoxymethimazole
- Carbimazolum
- Carbinazole
- Carbotiroid
- Mertiran
- Neomercazole
- TYRAZOL
- Thyrostat
- Carbimazol spofa
- CG1
- Cg 1
- Carbimazol henning (TN)
- Carbimazole (INN)
- Carbimazolum [INN-Latin]
- Neo-Mercazole
- Neo-Thyreostat
- Neo-Tireol
- Carbimazol [INN-Spanish, French]
- Carbimazole [INN:BAN:DCF]
- Ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate
- Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
- Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate
- 1-Ethoxycarbonyl-3-methyl-2-thioimidazol
- 1-Ethoxycarbonyl-3-methyl-2-thioxo-4-imidazoline
- 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo, ethyl ester
- 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester
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