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ZEBULARINE

SynDRA canonical compound SYN0018789 — structure-anchored drug synonym record

All known targets

• CDA
• DNMT1

Mechanisms of action (all sources)

• DNMT inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• HDAC6
• SIRT6
• SLC47A1
• SLC47A2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• KSYK
• SYK

Cross-references

• PubChem CID: 100016
• ChEMBL: CHEMBL504567
• DrugBank: DB03068
• ChEBI: 46938
• PDB: ZE8
• Wikipedia: Zebularine
• TTD: D0IF3H
• LINCS BRD: BRD-K87714311

Synonyms

• Pyrimidin-2-one ribonucleoside
• Pyrimidin-2-one beta-ribofuranoside
• Pyrimidin-2-one beta-D-ribofuranoside
• NSC 309132
• 4-Deoxyuridine
• CHEBI:46938
• 1-beta-D-ribofuranosylpyrimidin-2(1H)-one
• 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone
• UNII-7A9Y5SX0GY
• 7A9Y5SX0GY
• 2(1H)-Pyrimidinone, 1-beta-D-ribofuranosyl-
• 2-Pyrimidone-1-beta-D-riboside
• 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
• pyrimidin-2-one-ribonucleoside
• NSC-309132
• NSC309132
• RefChem:904822
• MFCD04973699
• NSC309132;4-Deoxyuridine
• 4-Deoyuridine
• 2(1H)-Pyrimidinone, 1-.beta.-D-ribofuranosyl-
• 4pd7
• 1-(beta-D-ribofuranosyl)pyrimidin-2(1H)-one
• URIDINE, 4-DEOXY-
• SCHEMBL13032
• GTPL4729
• orb1306235
• SCHEMBL29524837
• RPQZTTQVRYEKCR-WCTZXXKLSA-N
• GLXC-06602
• HMS3413C14
• HMS3677C14
• BDBM50226311
• HB1378
• 1-Pentofuranosylpyrimidin-2(1H)-one
• AKOS024457033
• Zebularine, >=98% (HPLC), solid