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SR-3677
SynDRA canonical compound SYN0018754 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ROCK2 |
|---|
| Mechanism of action | rho associated kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- rho associated kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CDC42BPA
- PRKACA
- AKT1
- ROCK1
- AAK1
- NTRK2
- PAK1
- OPRM1
- OPRD1
- NUAK2
- NUAK1
- NTRK3
- NR2C2
- NTRK1
- PAK3
- NPY2R
- NPY1R
- NLK
- NEK9
- NEK7
- NEK6
- NEK5
- PAK2
- PAK5
- PAK4
- PIK3CB
- PKMYT1
- PIP5K1A
- PIP4K2B
- PIM3
- PIM2
- PIM1
- PIK3CG
- PIK3CD
- PIK3CA
- NEK1
- PIK3C2B
- PHKG2
- PHKG1
- PDPK1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- SR3677
- MFCD16619390
- HMS3244C10
- JMC516642 Compound 5
- SCHEMBL453528
- orb1296145
- SCHEMBL29378608
- BDBM25474
- GLXC-04307
- HMS3244C09
- HMS3244D09
- EX-A1752
- AKOS027422764
- CS-1726
- SR3677?
- NCGC00345833-01
- NCGC00345833-06
- NCGC00345833-08
- AC-33204
- AS-16237
- HY-13300
- DB-059617
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