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AT-7519
SynDRA canonical compound SYN0018639 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
| Primary target(s) | CDK1 |
| Mechanism of action | Cell cycle inhibitor |
All known targets
- CDK2
- CDK1
- CDK9
- CDK6
- CDK5
- CDK4
- CDK8
- CDK7
- CDK3
- CDK20
- CDK19
- CDK10
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- Cell cycle inhibitor
- CDK1 INHIBITOR
- CDK4/6 inhibitor
- CDK2 INHIBITOR
- CDK5 INHIBITOR
- CDK7 INHIBITOR
- CDK3 INHIBITOR
- CDK16 INHIBITOR
- CDK18 INHIBITOR
- CDK8 INHIBITOR
- CDK17 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- MAPK8
- PIP4K2C
- PIP4K2B
- PIP4K2A
- PIM3
- PIM2
- PIM1
- PIK3CG
- PIK3CD
- PIK3CB
- PIK3CA
- PIK3C2G
- PIK3C2B
- PI4KB
- PHKG2
- PHKG1
- PGRMC1
- PFKP
- PEBP1
- PDXK
- PDPK1
- PDK1
- PDGFRB
- PDGFRA
- PASK
- PAK6
- PIP5K1A
- PIP5K1C
- PKMYT1
- PRKAR2A
- PRKD3
- PRKD2
- PRKD1
- PRKCZ
- PRKCQ
- PRKCI
- PRKCH
- PRKCE
- PRKCD
Cross-references
Synonyms
- AT 7519
- Cdki at7519
- AT7519
- LZE
- AT 7519, AT7519
- 4-[(2,6-dichlorobenzoyl)amino]-N-(4-piperidyl)-2H-pyrazole-3-carboxamide
- RefChem:560289
- AT-7519 free base
- AT7519 Hydrochloride
- MFCD13184820
- X1BF92PW9T
- UNII-X1BF92PW9T
- C16H17Cl2N5O2
- OVPNQJVDAFNBDN-UHFFFAOYSA-N
- pyrazole diamide, 33
- MLS006010064
- SCHEMBL955568
- GTPL5662
- JMC514986 Compound 33
- orb1300982
- SCHEMBL21134171
- BDBM24654
- CHEBI:91326
- EX-A225
- GLXC-90349
- HMS3265A09
- HMS3265A10
- HMS3265B09
- HMS3265B10
- HMS3654F20
- BDBM50113281
- EBC-11394
- NSC773394
- NSC799338
- s1524
- AKOS026674096
- AKOS037515688
- AT7519?
- CCG-264904
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