← SynDRA

PARTHENOLIDE

SynDRA canonical compound SYN0017692 — structure-anchored drug synonym record

All known targets

• HDAC1
• IKBKB
• NFKB1
• NFKB2
• REL
• RELA
• RELB

Mechanisms of action (all sources)

• NFkB pathway inhibitor
• IKBKB INHIBITOR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• HIF1A
• IL1B
• NSD2

Cross-references

• PubChem CID: 7251185
• ChEMBL: CHEMBL540445
• DrugBank: DB13063
• ChEBI: 7939
• KEGG: C07609
• RxNorm: 32941
• Wikipedia: Parthenolide
• TTD: D0M4KE

Synonyms

• NSC-157035
• (-)-Parthenolide
• CHEBI:7939
• Parthenolide, Tanacetum parthenium
• 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone
• partenolide
• C15H20O3
• Prestwick2_000550
• Prestwick3_000550
• Epitope ID:115014
• SCHEMBL8220
• BSPBio_001308
• BSPBio_000599
• MLS002153872
• CHEMBL465158
• BPBio1_000659
• SCHEMBL13367522
• BCBcMAP01_000041
• Parthenolide, &gt
• MolPort-008-268-168
• MolPort-003-959-089
• HMS1361B10
• HMS3402B10
• HMS1989B10
• HMS1791B10
• HMS1569N21
• HMS2096N21
• MFCD00134592
• (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1S,2R,4R,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one
• 2RDB26I5ZB
• NSC 157035
• PARTHENOLIDE [MI]
• PARTHENOLIDE [INCI]
• PARTHENOLIDE [USP-RS]
• PARTHENOLIDE [WHO-DD]
• parthenolide-(alternate-stereo)
• Parthenolide, >=98% (HPLC)