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AMOROLFINE
SynDRA canonical compound SYN0016559 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | membrane integrity inhibitor |
|---|
| Indication | onychomycosis |
|---|
| Disease area | infectious disease |
|---|
Mechanisms of action (all sources)
- membrane integrity inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ESR1
- ACHE
- TDP1
- TBXA2R
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- HTR2B
- ADORA3
- HTR1A
- HRH3
- HDAC6
- GMNN
- F2
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2A
- ADRA1A
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ANDR
- CP2C9
- CP2CJ
- CP2D6
- CP3A7
- ESRRA
- GLI3
- GPR32
- JUN
Drug classes
- Anti-Infective Agents
- Antifungal Agents
ATC classes
- D01A · ANTIFUNGALS FOR TOPICAL USE
Cross-references
Synonyms
- loceryl
- amorolfine hydrochloride
- amorolfine HCl
- Amorolfine hydrochloride
- Amorolfina
- Amorolfine (as hydrochloride)
- Amorolfine hcl
- RO-14-4767/000
- Loceryl
- Loceryl curanail
- Omicur
- Pekiron
- MT-861
- Amorolfine (cream, onychomycosis)
- Ro-14-4767
- Amorolfine (cream, onychomycosis), Roche
- Ro-14-4767/002
- Ro-14-4767/000
- AB0BHP2FH0
- Amorolfinum
- amorolfin
- Curanail
- Locetar
- Odenil
- DTXCID8026690
- CHEBI:599440
- Ro-14-4767-002
- amorolfine hydrochlorid
- RefChem:557892
- D01AE16
- imibenconazole-debenzyl
- NCGC00167524-01
- CAS-78613-35-1
- Loceryl (TN)
- Amorolfine Impurity 20
- Amorolfine (USAN/INN)
- SCHEMBL150666
- orb1710741
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