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TAZAROTENE
SynDRA canonical compound SYN0016463 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | RARG |
|---|
| Mechanism of action | Retinoid receptor agonist |
|---|
| Indication | cosmetic | sunscreen lotion |
|---|
| Disease area | dermatology |
|---|
All known targets
Mechanisms of action (all sources)
- Retinoid receptor agonist
- RARG AGONIST
- Retinoic acid receptor agonist
- RARB AGONIST
- RARA AGONIST
- RARG BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ESR1
- RXRA
- CYP3A4
- NR2C1
- NTHL1
- NR5A1
- NR4A1
- NR3C1
- NR2E1
- ADORA1
- NEIL2
- NEIL1
- MLNR
- MC4R
- MC3R
- MBD4
- MAOA
- NPY1R
- OPRD1
- OGG1
- SLC6A3
- UNG
- TDP1
- TDG
- TBXA2R
- SMUG1
- SLC6A4
- SLC6A2
- OPRK1
- SLC29A1
- PTGS2
- PGR
- PDE4D
- PDE3A
- OPRM1
- KMT2A
- HTR2C
- HTR3A
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP19A
- CP3A7
- ESRRA
- KSYK
- NF2L2
- NR1H4
- NR1I2
- PPARD
- SYK
- TP53
Drug classes
- Dermatologic Agents
- Keratolytic Agents
- Noxae
- Teratogens
- Retinoid
ATC classes
- D05A · ANTIPSORIATICS FOR TOPICAL USE
Cross-references
Synonyms
- ARAZLO
- AVAGE
- Arazlo
- DUOBRII
- Duobrii
- FABIOR
- Fabior
- HALOBETASOL PROPIONATE AND TAZAROTENE
- TAZORAC
- Tazorac
- tazorac
- fabior
- AGN-190168
- Tazaroteno
- Idp-123
- AGN190168
- Avage
- Tazarotene component of duobrii
- Tazarotene component of idp-118
- Zorac
- Suretin
- Tazarotenum
- Tazoral
- Avage (TN)
- Tazarotene [USAN:INN]
- Tazorac (TN)
- Zorac (TN)
- Tazarotene (JAN/USAN/INN)
- Tazorac, Avage, Zora, Tazarotene
- DUOBRII COMPONENT TAZAROTENE
- IDP-118 COMPONENT TAZAROTENE
- AGN 190168
- tazaroteno
- tazarotenum
- DTXCID3026691
- CHEBI:32184
- Tazaratone
Reported adverse events
- Sunburn
- Application site erythema
- Application site pain
- Application site pruritus
- Application site dryness
- Application site exfoliation
- Application site dermatitis
- Application site irritation
- Erythema
- Rash
- Cheilitis
- Dermatitis
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