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RIBAVIRIN
SynDRA canonical compound SYN0016059 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | IMPDH1 |
|---|
| Mechanism of action | Antiviral |
|---|
| Indication | hepatitis C |
|---|
| Disease area | infectious disease |
|---|
All known targets
- IMPDH1
- ADK
- ENPP1
- IMPDH2
- NT5C2
- ADORA1
- Adora1
- NS5B
- TOP1
- HCV NS3
Mechanisms of action (all sources)
- IMPDH1 INHIBITOR
- Inosine-5'-monophosphate dehydrogenase 1 inhibitor
- NS5B INHIBITOR
- HCV NS3 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- EIF4E
- NR1I2
- ABCB1
- MC5R
- MLNR
- MMP1
- MMP9
- NFE2L2
- NPY1R
- MC3R
- NPY2R
- NR1H4
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- MC4R
- MAPK3
- PDE4D
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- PDE3A
- PDE5A
- HRH1
- TACR1
- SLC6A2
- SLC6A3
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Nucleoside Analog Antiviral
- Anti-Infective Agents
- Antimetabolites
- Antiviral Agents
- Noxae
- Antiviral
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- COPEGUS
- REBETOL
- RIBASPHERE
- Ribasphere
- VIRAZOLE
- Virazole
- ribamide
- ribamidil
- ribavarin
- tribavirin
- Tribavirin
- Ribavirine
- Ribavirina
- Cotronak
- Ribavirin biopartners
- Ribavirin mylan
- Ribavirin teva
- NSC-163039
- SCH-18908
- Copegus
- Rebetol
- Ribapak
- Ribavarin
- Ribavirin mylan (previously ribavirin three rivers)
- Ribavirin teva pharma b.v.
- Ribofluranosyl carboxamide
- Viramid
- Virazid
- Vilona
- Ribamide
- Ribamidil
- Ribamidyl
- Ribavirinum
- Rebetron
- Varazid
- RTCA
- Ribavirin Capsules
Reported adverse events
- Hemolytic anemia
- Rash
- Seizure
- Cardiac arrest
- Death
- Alopecia
- Arthralgia
- Depression
- Fatigue
- Headache
- Pruritus
- Asthenia
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