← SynDRA
PREDNISOLONE HEMISUCCINATE
SynDRA canonical compound SYN0015623 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
All known targets
- NR3C1
- PLA2G1B
- NR3C2
- SERPINA6
- HSD11B1
- ESRRA
- ESRRB
- ESRRG
- ANXA1
- AR
- IL6
- GPBAR1
Mechanisms of action (all sources)
- NR3C1 AGONIST
- Phospholipase activator
- NR3C1 FULL AGONIST
- NR3C1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CBX1
- HDAC6
- HIF1A
- IDH1
- LMNA
- NFE2L2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Glucocorticoids
- Hormones
- Anti-Inflammatory Agents
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Alkylating Activity
- Alkylating Drug
- Alkylating Agents
- Antineoplastic Agents, Alkylating
- Noxae
ATC classes
- S02B · CORTICOSTEROIDS
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- A01A · STOMATOLOGICAL PREPARATIONS
- D07A · CORTICOSTEROIDS, PLAIN
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- L01A · ALKYLATING AGENTS
- A07E · INTESTINAL ANTIINFLAMMATORY AGENTS
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- S01B · ANTIINFLAMMATORY AGENTS
- S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
Cross-references
Synonyms
- prednisolone succinate
- prednisolone bisuccinate
- prednisolone sodium succinate
- Prednisolone succinate
- Prednisolone hydrogen succinate
- NSC-759137
- BRD-K09295900
- prednisolone.hemisuccinate
- Prednisolone 21-hemisuccinate
- Prednisolut
- Prednisolone bisuccinate
- Prednisolone (hemisuccinate)
- Prednisolone 21-succinate
- Prednisolone 21-(hydrogen succinate)
- (+)-prednisolone hemisuccinate
- Prednisolone hemisuccinate [USP]
- G7080T74ON
- Prednisolonbisuccinat
- Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11beta)-
- NSC 759137
- 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
- 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(hydrogen succinate)
- Prednisolone hemisuccinate (USP)
- Prednisolonbisuccinat [German]
- UNII-G7080T74ON
- NCGC00183124-01
- EINECS 220-861-8
- Prednisolonhemisuccinat
- SCHEMBL139689
- CHEMBL485659
- Prednisolone succinate (JP17)
- DTXSID1048964
- CHEBI:135745
- Delta(1)-hydrocortisone succinate
- HY-B1087
- ZINC3881478
- PREDNISOLONE SUCCINATE [JAN]
- Tox21_113404
Reported adverse events
- Cushingoid
- Exophthalmos
- Fluid retention
- Urticaria
- Hypertension
- Sodium retention
- Petechiae
- Headache
- Vertigo
- Glaucoma
- Infection
- Tendon rupture
Look up PREDNISOLONE HEMISUCCINATE in the interactive SynDRA portal →