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VERUBULIN
SynDRA canonical compound SYN0014352 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | TUBB |
|---|
| Mechanism of action | tubulin polymerization inhibitor |
|---|
All known targets
- TUBB
- TUBA1A
- TUBA1B
- TUBA1C
- TUBA3C
- TUBA3E
- TUBA4A
- TUBB1
- TUBB2A
- TUBB2B
- TUBB3
- TUBB4A
Mechanisms of action (all sources)
- TUBB4B DISRUPTING AGENT
- TUBB1 DISRUPTING AGENT
- TUBA3C DISRUPTING AGENT
- TUBA4A DISRUPTING AGENT
- TUBB3 DISRUPTING AGENT
- TUBA1A DISRUPTING AGENT
- TUBB4A DISRUPTING AGENT
- TUBB8 DISRUPTING AGENT
- TUBB DISRUPTING AGENT
- TUBA1B DISRUPTING AGENT
- TUBA1C DISRUPTING AGENT
- TUBA3E DISRUPTING AGENT
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Verubuline
- Verubulina
- MPC-6827
- MX-128495
- Azixa
- Verubulin hydrochloride
- EP-128495
- Apoptosis inducer (cancer), Myriad
- Caspase inducer (cancer), Myriad
- Cell cycle arrest inducer (cancer), Myriad
- Tubulin inhibitor (cancer), Myriad
- N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine
- MPC-6827 (hydrochloride)
- X97O9FTB92
- Verubulin (hydrochloride)
- N-(4-methoxyphenyl)-N,2-dimethyl-quinazolin-4-amine
- Verubulin [USAN]
- Verubulin [USAN:INN]
- Verubulin, MPC-6827
- UNII-X97O9FTB92
- VERUBULIN [INN]
- Verubulin (USAN/INN)
- VERUBULIN [WHO-DD]
- 4-Quinazolinamine, N-(4-methoxyphenyl)-N,2-dimethyl-
- CHEMBL492399
- SCHEMBL2232326
- AMY32185
- BCP09127
- CIB03183
- BDBM50557539
- NSC758773
- ZINC35978229
- AKOS015994561
- DB05585
- EE-0048
- NSC-758773
- SB19790
- NCGC00387248-01
- AC-25267
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