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PALIPERIDONE

SynDRA canonical compound SYN0014173 — structure-anchored drug synonym record

All known targets

• HTR2A
• DRD2
• HTR1A
• HTR7
• HTR1E
• HRH1
• HTR1D
• HTR1B
• ADRA1A
• PTGER3
• KCNH2
• HTR6

Mechanisms of action (all sources)

• DRD2 ANTAGONIST
• Dopamine D2 receptor antagonist
• HTR2A ANTAGONIST
• Serotonin 2a (5-HT2a) receptor antagonist
• dopamine receptor antagonist
• serotonin receptor antagonist
• HTR1A ANTAGONIST
• HTR1D ANTAGONIST
• HTR1E ANTAGONIST
• HRH1 ANTAGONIST
• HTR1B ANTAGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ABCB1
• ARSA
• EHMT2
• HDAC6
• KAT2A
• KCND3
• POU2F1
• SCN5A
• SLC22A3
• SLC47A1
• SLC47A2
• TDP1

Drug classes

• Atypical Antipsychotic
• Antipsychotic Agents
• Central Nervous System Agents
• Central Nervous System Depressants
• Dopamine Agents
• Dopamine Antagonists
• Dopamine D2 Receptor Antagonists
• Neurotransmitter Agents
• Psychotropic Drugs
• Serotonin 5-HT2 Receptor Antagonists
• Serotonin Agents
• Serotonin Antagonists

ATC classes

• N05A · ANTIPSYCHOTICS

Cross-references

• PubChem CID: 115237
• ChEMBL: CHEMBL1621
• DrugBank: DB01267
• ChEBI: CHEBI:82978
• KEGG: D05339
• RxNorm: 679314
• Wikipedia: Paliperidone
• TTD: D0B3UJ

Synonyms

• ERZOFRI
• Erzofri
• INVEGA
• INVEGA HAFYERA
• INVEGA SUSTENNA
• INVEGA TRINZA
• Invega
• RO76477
• RO 76477
• invega
• xeplion
• Paliperidona
• 9-hydroxyrisperidone
• NSC-759623
• R-76477
• RO-76477
• Risperidone impurity, 9-hydroxyrisperidone-
• Xeplion
• Invega Sustenna
• Paliperidone palmitate
• JNS-010
• Paliperidone (depot injection, NanoCrystal)
• Paliperidone (injectable, NanoCrystal), Elan
• Paliperidone (depot injection, NanoCrystal), Johnson & Johnson
• 9-Hydroxyrisperidone
• 9-OH-risperidone
• C23H27FN4O3
• R 76477
• CHEMBL1621
• CHEBI:83804
• 144598-75-4 (free base)
• NSC 759623
• 838F01T721
• Paliperidone [INN]
• PALLIPERIDONE
• 9-hydroxy risperidone
• HSDB 8148