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NEFOPAM
SynDRA canonical compound SYN0011990 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | cyclooxygenase inhibitor |
|---|
| Indication | pain relief |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR2A
- HTR2B
- HTR2C
- SCN5A
- SLC6A2
- SLC6A3
- SLC6A4
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM1
- CHRM3
- HRH1
- ADRA2B
- KCNH2
- ESR1
- OPRM1
- OPRK1
- HTR3A
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- ADORA1
- OPRD1
- HRH3
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLCO1B1
- SLCO1B3
- SMN1
- TBXA2R
- HTR1A
- HDAC6
- HRH2
- ADORA2A
- ADORA3
- ADRA2A
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- BDKRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Central Nervous System Agents
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- N02B · OTHER ANALGESICS AND ANTIPYRETICS
Cross-references
Synonyms
- fenazoxine
- (+/-)-Nefopam
- nefopam hydrochloride
- nefopam HCl
- Nefopam hydrochloride
- Nefopam HCl
- 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride
- Acupan
- Nefopam (hydrochloride)
- Ajan
- Pallopikeron
- Leoplexamin
- Lenipan
- Sinalgico
- Oxadol
- Fenazoxine hydrochloride
- Nefopam hydrochloride [USAN]
- EINECS 245-585-5
- 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine hydrochloride
- DSSTox_CID_25441
- DSSTox_RID_80882
- DSSTox_GSID_45441
- Nefopam hydrochloride (USAN)
- R 738
- 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine
- Fenazoxine
- Nefopamum
- 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-
- 4UP8060B7J
- 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocin
- Nefopam, Silentan
- RefChem:832138
- DTXCID8028002
- CHEBI:88316
- N02BG06
- 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine
- 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
- CHEBI:88318
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