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CEDIRANIB
SynDRA canonical compound SYN0011957 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | PDGFRB |
|---|
| Mechanism of action | VEGFR inhibitor |
|---|
All known targets
- KDR
- FLT1
- FLT4
- KIT
- PDGFRB
- PDGFRA
- CSF1R
- FLT3
Mechanisms of action (all sources)
- KIT INHIBITOR
- VEGFR inhibitor
- Stem cell growth factor receptor inhibitor
- PDGFRB INHIBITOR
- Platelet-derived growth factor receptor inhibitor
- PDGFRA INHIBITOR
- FLT1 INHIBITOR
- Vascular endothelial growth factor receptor inhibitor
- FLT4 INHIBITOR
- KDR INHIBITOR
- CSF1R INHIBITOR
- FLT3 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MERTK
- TGFBR1
- PLK4
- STK33
- STK35
- EGFR
- EIF2AK1
- GAK
- STK4
- FYN
- SYK
- TAOK1
- TAOK2
- TAOK3
- MAP4K2
- MAP4K3
- TEK
- MAP4K4
- BTK
- STK3
- STK26
- MAP3K19
- LTK
- CSNK1E
- RIPK2
- RET
- LCK
- SIK2
- DDR1
- CHEK2
- LYN
- STK10
- SLK
- DDR2
- MAP2K2
- SRC
- MAP2K5
- HCK
- PTK6
- MAP4K5
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ATXN2
- HLAB
- IFNB1
- KCC2B
- KPCD2
- KSYK
- M4K2
- M4K4
- M4K5
- MP2K2
- NSD2
- NTM1A
- NTMT1
- TP53
Drug classes
- Antineoplastic Agents
- Protein Kinase Inhibitors
ATC classes
- L01E · PROTEIN KINASE INHIBITORS
Cross-references
Synonyms
- AZD-2171
- AZD2171
- ZD-2171
- Recentin
- M6294
- AZD2171, Recentin, Cediranib
- Cediranib (USAN/INN)
- 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline
- 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline
- Cedirannib
- Cediranib (AZD2171)
- 4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline
- Cediranib free base
- 4-(4-Fluoro-2-methylindol-5-yloxy)-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline
- AZD-2171 maleate
- NQU9IPY4K9
- ZD 2171
- CHEMBL491473
- 288383-20-0 (free base)
- NSC-732208
- 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline
- Cediranib (AZD217)
- Cediranib [INN]
- Kinome_3318
- UNII-NQU9IPY4K9
- Cediranib [USAN:INN:BAN]
- 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline
- 4-((4-FLUORO-2-METHYL-1H-INDOL-5-YL)OXY)-6-METHOXY-7-(3-PYRROLIDIN-1-YLPROPOXY)QUINAZOLINE
- Quinazoline, 4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(1-pyrrolidinyl)propoxy)-
- Quinazoline, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-
- Cediranib,AZD2171
- Cediranib dihydrochloride
- AZD2171, Cediranib
- CEDIRANIB [USAN]
- Cediranib - AZD2171
- CEDIRANIB [MART.]
- CEDIRANIB [WHO-DD]
- SCHEMBL63147
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