← SynDRA
BMS-777607
SynDRA canonical compound SYN0011935 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | TYRO3 |
|---|
| Mechanism of action | Hepatocyte growth factor receptor inhibitor |
|---|
All known targets
- MET
- AXL
- MERTK
- MST1R
- TYRO3
- FLT3
Mechanisms of action (all sources)
- FLT3 INHIBITOR
- MET INHIBITOR
- AXL kinase inhibitor
- Macrophage inhibitor
- tyrosine kinase inhibitor
- Hepatocyte growth factor receptor inhibitor
- AXL INHIBITOR
- MST1R INHIBITOR
- MERTK INHIBITOR
- TYRO3 INHIBITOR
- macrophage migration inhibiting factor inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AURKB
- MAP2K5
- FRK
- PDE4D
- PDGFRA
- RET
- KDR
- SYK
- KIT
- LCK
- NTRK2
- DDR1
- DDR2
- NTRK1
- PLK4
- MAP4K2
- YES1
- ABL1
- ABL2
- PRKACA
- PAICS
- PAK4
- PAK2
- PKN2
- PDXK
- OPA1
- OLA1
- OGG1
- NUAK2
- NTRK3
- PDGFRB
- PEBP1
- PRKACG
- PLK1
- PFKP
- PRKACB
- PHKG2
- PRKAA1
- PIM1
- PIP4K2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- ASLAN-002
- ASLAN002
- BMS 777607
- BMS777607
- UNII-A3MMS6HDO1
- N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
- A3MMS6HDO1
- N-[4-[(2-Amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
- N-(4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
- RefChem:120741
- DTXCID0067769
- MET Tyrosine Kinase Inhibitor BMS-777607
- MFCD16495773
- BMS 817378
- C25H19ClF2N4O4
- VNBRGSXVFBYQNN-UHFFFAOYSA-N
- MLS006010958
- orb322920
- GTPL7953
- orb1305149
- SCHEMBL2588311
- SCHEMBL29391695
- SCHEMBL29428132
- BDBM28031
- CHEBI:91409
- EX-A004
- 3f82
- GLXC-08078
- HMS3295I07
- HMS3655C05
- NSC764090
- NSC799365
- s1561
- BMS 777607 [WHO-DD]
- AKOS026750587
- BMS777607?
- CCG-264913
- CS-0227
Look up BMS-777607 in the interactive SynDRA portal →