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QUINAPRIL
SynDRA canonical compound SYN0011847 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACE |
|---|
| Mechanism of action | Angiotensin converting enzyme inhibitor |
|---|
| Indication | angioedema | congestive heart failure | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- ACE inhibitor
- SLC33A1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- HTR6
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR7
- HTR5A
- ABCC2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- GIPR
- GHSR
- GCGR
- NPY1R
- NPY2R
- NR3C1
- NTSR1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- GEMI
- GLI3
- JUN
- KSYK
- NR1I2
- SYK
- TSHR
Drug classes
- Angiotensin-converting Enzyme Inhibitors
- Angiotensin Converting Enzyme Inhibitor
- Antihypertensive Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Protease Inhibitors
ATC classes
- C09A · ACE INHIBITORS, PLAIN
- ACE INHIBITORS, COMBINATIONS
Cross-references
Synonyms
- ACCUPRIL
- ACCURETIC
- Accupril
- QUINAPRIL HYDROCHLORIDE
- QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
- ectren
- koretic
- quinapril hydrochloride
- quinapril HCl
- C09AA06
- Ectren
- Koretic
- Quinaprilum
- QUINAPRIL HCL
- Quinaprilum [Latin]
- Accupril (TN)
- Quinapril [INN:BAN]
- Quinapril (USP/INN)
- quinapril (usp impurity)
- RJ84Y44811
- CHEBI:8713
- RefChem:57154
- DTXCID303547
- PD 1094522
- PD 109452-2
- PD-109,452-2
- Accuretic
- Quinapril (INN)
- QUINAPRIL [INN]
- CI-906 (free acid)
- Quinapril [USP:INN:BAN]
- UNII-RJ84Y44811
- Quinapril (Korec)
- Spectrum_001597
- QUINAPRIL [MI]
- Spectrum2_000825
- Spectrum3_001551
- Spectrum4_000727
Reported adverse events
- Cough
- Dizziness
- Fatigue
- Headache
- Nausea
- Vomiting
- Myalgia
- Hypotension
- Rash
- Alopecia
- Bradycardia
- Gastrointestinal carcinoma
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