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ACETOHEXAMIDE

SynDRA canonical compound SYN0011820 — structure-anchored drug synonym record

All known targets

• ABCC8
• KCNJ11
• KCNJ1
• KCNJ10

Mechanisms of action (all sources)

• KCNJ11 BLOCKER
• Sulfonylurea receptor 1, Kir6.2 blocker
• ABCC8 BLOCKER
• ATP channel blocker
• ABCC8 MODULATOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ADORA1
• LMNA
• NPY1R
• NFE2L2
• MLNR
• MC4R
• MC3R
• MAOA
• KCNH2
• NR1I2
• KAT2A
• HTR3A
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• NR1H4
• NR3C1
• HRH1
• SLC29A1
• THRB
• TDP1
• TBXA2R
• SLC6A4
• SLC6A3
• SLC6A2
• SAMHD1
• OPRD1
• PTGS2
• PGR
• PDE4D
• PDE3A
• OPRM1
• OPRK1
• HRH2
• HDAC6
• ADORA2A
• AGTR1
• BLM
• BDKRB2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2C9
• CP2D6

Drug classes

• Hypoglycemic Agents

ATC classes

• A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS

Cross-references

• PubChem CID: 1989
• ChEMBL: CHEMBL1589
• DrugBank: DB00414
• ChEBI: CHEBI:28052
• KEGG: D00219
• RxNorm: 173
• PDB: TF9
• Wikipedia: Acetohexamide
• TTD: D07WFK
• LINCS BRD: BRD-K52960356

Synonyms

• DYMELOR
• dymelor
• acetohexamid
• Acetohexamida
• 33006
• NSC-759128
• Dimelor
• Dymelor
• Acetohexamid
• Acetohexamidum
• Dimelin
• Gamadiabet
• Hypoglicil
• Metaglucina
• Minoral
• Ordimel
• Tsiklamid
• Acetohexamide Lilly Brand
• Acetohexamide Salvat Brand
• Lilly Brand of Acetohexamide
• Ord imel
• Salvat Brand of Acetohexamide
• U-14812
• A-178
• Acetohexamida [INN-Spanish]
• Acetohexamidum [INN-Latin]
• Dimelin (antidiabetic)
• Dymelor (TN)
• Acetohexamide (JP15/USP/INN)
• Acetohexamide [USAN:INN:BAN:JAN]
• N-(p-Acetylbenzenesulfonyl)-N'-cyclohexylurea
• N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea
• 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea
• 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
• 1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea
• 3-cyclohexyl-1-(p-acetylphenylsulfonyl)urea
• 4-Acetyl-N-((cyclohexylamino)carbonyl)benzenesulfonamide