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NITRENDIPINE
SynDRA canonical compound SYN0011744 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CACNA2D1 |
|---|
| Mechanism of action | Calcium channel blocker |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- CACNA1D
- CACNA1C
- CACNA1F
- CACNA2D1
- KCNN4
- CACNA1S
- ABCG2
- Cacna1s
- SCN3A
- SCN2A
- SCN1A
- PTAFR
Mechanisms of action (all sources)
- Calcium channel blocker
- CACNA1C BLOCKER
- Voltage-gated L-type calcium channel blocker
- CACNA1S BLOCKER
- CACNA1D BLOCKER
- CACNA1F BLOCKER
- CACNA1D INHIBITOR
- CACNA1F ANTAGONIST
- KCNN4 INHIBITOR
- CACNA2D1 BLOCKER
- CACNA1D GATING INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- SCN5A
- ABCB1
- MTOR
- MLNR
- MMP1
- MMP9
- MPG
- MPHOSPH8
- NEIL1
- MUTYH
- NEIL2
- NPY1R
- NPY2R
- NR3C1
- NTHL1
- MC5R
- MC4R
- OGG1
- LCK
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- HTR6
- LMNA
- MC3R
- MAOA
- MAPK1
- MAPK14
- MAPK3
- MAPT
- MBD4
- NTSR1
- OPRD1
- HRH2
- SLC29A1
- VDR
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- GCR
- GPR55
- HLAB
- IFNB1
- NR1H4
- PRGR
- PRKN
- RAPGEF4
- RPGF4
- TARDBP
Drug classes
- Antihypertensive Agents
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Membrane Transport Modulators
- Vasodilator Agents
ATC classes
- C08C · SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
- ACE INHIBITORS, COMBINATIONS
Cross-references
Synonyms
- nitrendipin
- nitrepin
- Nitrendipino
- Bayotensin
- Deiten
- Nidrel
- Nitrepin
- (+/-)-BAY-E-5009
- BAY-E-5009
- NSC-758466
- Baypress
- Baylotensin
- Bylotensin
- Gericin
- Jutapress
- Niprina
- NitrePuren
- Nitregamma
- Nitrendepat
- Nitrendidoc
- Nitrendimerck
- Nitrendipin
- Nitrendipincorax
- Nitrendipinum
- Nitrensal
- Nitrepress
- Tensogradal
- Trendinol
- Vastensium
- Nitre AbZ
- Nitre-Puren
- Nitren Lich;Nitren acis
- Nitrend KSK
- Nitrendi Biochemie
- Nitrendipin AL
- Nitrendipin Apogepha
- Nitrendipin Atid
- Nitrendipin Basics
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