← SynDRA
LACIDIPINE
SynDRA canonical compound SYN0011726 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CACNA1C |
|---|
| Mechanism of action | calcium channel blocker |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- CACNA1C
- CACNA1D
- CACNA1F
- CACNA1S
- ADORA3
- Ar
- CYP2C19
- CYP2C9
- CYP3A4
- DRD3
- SLC6A2
- TBXAS1
Mechanisms of action (all sources)
- CACNA1C BLOCKER
- Voltage-gated L-type calcium channel blocker
- CACNA1S BLOCKER
- CACNA1D BLOCKER
- CACNA1F BLOCKER
- calcium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- OPRK1
- ESR1
- MAOA
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- LCK
- NPY2R
- KCNH2
- IDO1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- NPY1R
- ACHE
- HMGCR
- PTPRC
- TDP1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC29A1
- SIGMAR1
- SCN5A
- SAMHD1
- PTGS2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- KSYK
- TP53
- SYK
- SMAD3
- SMAD2
- RARA
- PRGR
- PPARG
- PPARD
- NTR1
- NSD2
- NR1H4
- NF2L2
- MDM4
- MDM2
- KCNQ1
- ANDR
- HSPB1
- HIF1A
- GLI3
- ESRRA
- CP3A7
- CP3A4
- CP2CJ
- CP2C9
- CP19A
- CASP7
- CASP3
- CAC1H
- ATXN2
- ATF6
- VDR
Drug classes
- Antihypertensive Agents
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Membrane Transport Modulators
ATC classes
- C08C · SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Cross-references
Synonyms
- lacipil
- lacirex
- GR-43659X
- motens
- Lacidipino
- 3,3'-iminobispropylamine
- 3,3'-iminodipropylamine
- 4-azaheptamethylenediamine
- Dipropylamine, 3,3'-diamino-
- Dipropylenetriamine
- NSC-7773
- Caldine
- Molap
- Motens
- Lacipil
- GR 43659X
- Lacidipinum
- DTXCID9026429
- RefChem:924456
- C08CA09
- MFCD00865936
- GX 1048
- C26H33NO6
- Lacimen
- Lacidipinum [Latin]
- Lacidipino [Spanish]
- Lacirex
- SMR000466342
- CAS-103890-78-4
- SR-05000001445
- GR 43659 X
- Viapres
- Lacidipine (Lacipil, Motens)
- Lacidipine [USAN:INN:BAN]
- NCGC00164545-01
- Motens (TN)
- SN-305
- UNII-260080034N
Look up LACIDIPINE in the interactive SynDRA portal →