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METAMIZOLE
SynDRA canonical compound SYN0011699 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | PTGS1 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Opioid receptor agonist
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- TRPA1 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ACHE
- KCNH2
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KDM4E
- KAT2A
- MMP9
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- MMP1
- NPY1R
- FYN
- PTPRC
- USP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- GNAI1
- GPX1
- GPX4
- LOX12
- LOX15
- RGS12
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antipyretics
- Antirheumatic Agents
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- N02B · OTHER ANALGESICS AND ANTIPYRETICS
Cross-references
Synonyms
- algocalmin
- metamizole sodium
- metamizol
- metapyrin
- methampyrone
- dipyrone
- dipyrone monohydrate
- sulpyrine
- metamizole magnesium
- metamizole calcium
- Dipyrone free acid anhydrous
- Methamizole-
- Dipyrone
- Analgin
- Metamizole sodium
- Methampyrone
- Novalgin
- Neomelurbrin
- Methylmelubrin
- Algocalmin
- Optalgin
- Novalgetol
- Sulpyrin
- Pyralgin
- Narone
- Novaminsulfone
- Novamidazophen
- Nevralgina
- Pharmalgine
- Algopyrine
- Farmolisina
- Pyretin
- Keypyrone
- Analgine
- Noveltex
- Fevonil
- Diprofarn
- Dimethone
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